IFNGR2 and RPL37A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		IFNGR2	RPL37A
Gene Name		interferon gamma receptor 2 (interferon gamma transducer 1)	ribosomal protein L37a
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Nucleus Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Cytokine Receptor Activity Interferon-gamma Receptor Activity	Structural Constituent Of Ribosome Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Response To Virus Cytokine-mediated Signaling Pathway Interferon-gamma-mediated Signaling Pathway Regulation Of Interferon-gamma-mediated Signaling Pathway	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Regulation of IFNG signaling	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs		Interferon gamma-1b
Diseases
GWAS		Crohn's disease ( 22936669 23128233) Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: ANXA5 CAMK2D DNAJA3 IFNG IFNGR1 JAK2 NR3C1 RPL37A	7 interactors: APP BUB3 CTPS2 IFNGR2 LRIF1 MAGEA6 NKX3-1
Entrez ID		3460	6168
HPRD ID		00956	17997
Ensembl ID		ENSG00000159128
Uniprot IDs		A8K881 E7EUY1 P38484	P61513
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Response To Interferon-gamma Regulation Of Cytokine-mediated Signaling Pathway Interferon-gamma-mediated Signaling Pathway Cellular Response To Interferon-gamma Regulation Of Innate Immune Response Response To Organic Substance Response To Cytokine Innate Immune Response Cytokine-mediated Signaling Pathway Regulation Of Heart Contraction Cellular Response To Cytokine Stimulus Immune Response Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Defense Response Positive Regulation Of Cell Death Positive Regulation Of Interleukin-1 Beta Production Regulation Of Apoptotic Process Positive Regulation Of Phosphatase Activity Regulation Of The Force Of Heart Contraction Positive Regulation Of Interleukin-1 Production Regulation Of Cell Death Homeostasis Of Number Of Cells Regulation Of Signal Transduction Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Cell Proliferation Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Proteolysis Positive Regulation Of Cell Activation Regulation Of Signaling Regulation Of Immune Response Positive Regulation Of Dephosphorylation Regulation Of Interleukin-1 Beta Production Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Tumor Necrosis Factor Production Establishment Of Protein Localization To Organelle Signal Transduction Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of JAK-STAT Cascade Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Stress Regulation Of Steroid Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Signaling	Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction 'de Novo' CTP Biosynthetic Process Positive Regulation Of Androgen Secretion Regulation Of Proteolysis Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Collateral Sprouting In Absence Of Injury Negative Regulation Of Estrogen Receptor Binding Collateral Sprouting Axon Midline Choice Point Recognition Intracellular Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Axon Choice Point Recognition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Receptor Binding Regulation Of Cell Division Regulation Of Binding Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Neuron Remodeling Positive Regulation Of Cell Cycle Dorsal Aorta Development Positive Regulation Of Proteolysis Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Attachment Of Spindle Microtubules To Kinetochore
Tagcloud ?		allelic candidiasis cybb definition designation errors il12b il12rb1 immunological impair inborn intramacrophagic irf8 isg15 mendelian msmd mycobacteria nemo overt parasites penetrance perhaps physiologically predisposition recapitulate salmonellosis virulent weakly	3d actb algorithms aspirates calculating cancellous cd71 cube cultivated cultivation genorm hprt1 hypoxanthine mscs normfinder osteogenic phosphoribosyltransferase porous prerequisite qrt rgs scaffolds stably taqman tata tbp te tfrc
Tagcloud (Difference) ?		allelic candidiasis cybb definition designation errors il12b il12rb1 immunological impair inborn intramacrophagic irf8 isg15 mendelian msmd mycobacteria nemo overt parasites penetrance perhaps physiologically predisposition recapitulate salmonellosis virulent weakly	3d actb algorithms aspirates calculating cancellous cd71 cube cultivated cultivation genorm hprt1 hypoxanthine mscs normfinder osteogenic phosphoribosyltransferase porous prerequisite qrt rgs scaffolds stably taqman tata tbp te tfrc
Tagcloud (Intersection) ?