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RPL18A and MAP3K12
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
RPL18A
MAP3K12
Gene Name
ribosomal protein L18a
mitogen-activated protein kinase kinase kinase 12
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Membrane
Cytosolic Large Ribosomal Subunit
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Axon
Growth Cone
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Poly(A) RNA Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Protein Homodimerization Activity
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Translation
Translational Initiation
Translational Elongation
Translational Termination
SRP-dependent Cotranslational Protein Targeting To Membrane
Gene Expression
Viral Process
Viral Life Cycle
Viral Transcription
Cellular Protein Metabolic Process
Activation Of MAPKK Activity
Protein Phosphorylation
JNK Cascade
Histone Phosphorylation
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Intracellular Signal Transduction
Protein Autophosphorylation
Pathways
Nonsense-Mediated Decay (NMD)
Translation
SRP-dependent cotranslational protein targeting to membrane
Eukaryotic Translation Termination
Peptide chain elongation
Influenza Infection
Viral mRNA Translation
L13a-mediated translational silencing of Ceruloplasmin expression
Influenza Life Cycle
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Influenza Viral RNA Transcription and Replication
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Initiation
Formation of a pool of free 40S subunits
Eukaryotic Translation Elongation
Cap-dependent Translation Initiation
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
AES
JUN
LPL
MAP3K12
MDK
NEDD4
RIBC2
RNF115
RPL36
TNK2
15 interactors:
EGFR
FRA10AC1
FTL
MAP2K4
MAP2K7
MAP3K11
MAPK6
MAPK8IP1
MAPK8IP2
MBIP
RGS1
RPL18A
SH3RF1
TGM2
TSC22D1
Entrez ID
6142
7786
HPRD ID
16045
02709
Ensembl ID
ENSG00000105640
ENSG00000139625
Uniprot IDs
B4DM94
Q02543
Q12852
PDB IDs
3J3B
Enriched GO Terms of Interacting Partners
?
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein K63-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Outflow Tract Morphogenesis
Establishment Of Protein Localization To Organelle
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Defecation
Cellular Response To Potassium Ion Starvation
Transmission Of Virus
Development Involved In Symbiotic Interaction
Protein Targeting
Response To Radiation
Response To Stress
Signal Transduction
Negative Regulation Of Binding
Response To Drug
Protein Localization To Organelle
Leading Edge Cell Differentiation
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Response To Calcium Ion
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Signaling
Cell Communication
Chylomicron Remodeling
Positive Regulation Of Anoikis
Regulation Of Signal Transduction
Protein Polyubiquitination
Cytoplasmic Transport
Negative Regulation Of Neuron Apoptotic Process
Response To Cytokine
Progesterone Receptor Signaling Pathway
Positive Regulation Of Monocyte Differentiation
Positive Regulation Of Sequestering Of Triglyceride
Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Stimulus
Negative Regulation Of Neuron Death
Protein Autophosphorylation
Cellular Response To Extracellular Stimulus
Regulation Of Signaling
Catabolic Process
Heart Morphogenesis
Cell Surface Receptor Signaling Pathway
Glucocorticoid Receptor Signaling Pathway
SMAD Protein Import Into Nucleus
Very-low-density Lipoprotein Particle Remodeling
MAPK Cascade
Cellular Macromolecule Catabolic Process
MAPK Cascade
Signal Transduction By Phosphorylation
Regulation Of JNK Cascade
Regulation Of MAPK Cascade
Regulation Of Stress-activated MAPK Cascade
JNK Cascade
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Regulation Of MAP Kinase Activity
Regulation Of Protein Kinase Activity
Regulation Of Intracellular Signal Transduction
Regulation Of Kinase Activity
Regulation Of JUN Kinase Activity
Regulation Of Phosphorylation
Regulation Of Signal Transduction
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Cell Death
Regulation Of Signaling
Regulation Of Protein Phosphorylation
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Catalytic Activity
Activation Of JUN Kinase Activity
Cellular Response To Sorbitol
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of MAPK Cascade
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Neuron Apoptotic Process
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of Kinase Activity
Peptidyl-amino Acid Modification
Regulation Of Protein Metabolic Process
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of Neuron Death
Positive Regulation Of Transferase Activity
Positive Regulation Of Apoptotic Process
Activation Of Protein Kinase Activity
Positive Regulation Of Programmed Cell Death
Cellular Protein Modification Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Cell Death
Cellular Protein Metabolic Process
Phosphorylation
Intracellular Signal Transduction
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of JNK Cascade
Tagcloud
?
adipocytes
adipogenesis
adipogenic
adipose
ascs
bisphenol
bpa
ccaat
cebpa
disrupter
dlk
dye
ebpalpha
esr1
ici
igf1
leucine
lipase
lpl
peroxisome
physiologically
pparg
ppargamma
precursors
proliferator
retained
temporally
visualize
zipper
Tagcloud (Difference)
?
adipocytes
adipogenesis
adipogenic
adipose
ascs
bisphenol
bpa
ccaat
cebpa
disrupter
dlk
dye
ebpalpha
esr1
ici
igf1
leucine
lipase
lpl
peroxisome
physiologically
pparg
ppargamma
precursors
proliferator
retained
temporally
visualize
zipper
Tagcloud (Intersection)
?