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RPL10 and HCK
Number of citations of the paper that reports this interaction (PubMedID
12138090
)
0
Data Source:
BioGRID
(pull down)
RPL10
HCK
Description
ribosomal protein L10
HCK proto-oncogene, Src family tyrosine kinase
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum
Smooth Endoplasmic Reticulum
Cytosol
Ribosome
Membrane
Cytosolic Large Ribosomal Subunit
Cytosolic Ribosome
Protein-containing Complex
Ribonucleoprotein Complex
Nucleus
Cytoplasm
Lysosome
Golgi Apparatus
Cytosol
Cytoskeleton
Actin Filament
Plasma Membrane
Caveola
Focal Adhesion
Cytoplasmic Side Of Plasma Membrane
Membrane
Transport Vesicle
Cytoplasmic Vesicle
Cell Projection
Membrane Raft
Anchoring Junction
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Translation Regulator Activity
Nucleotide Binding
Phosphotyrosine Residue Binding
Protein Kinase Activity
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Signaling Receptor Binding
Protein Binding
ATP Binding
Lipid Binding
Kinase Activity
Transferase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Cytoplasmic Translation
Translation
Regulation Of Translation
Negative Regulation Of Apoptotic Process
Embryonic Brain Development
Immune System Process
Leukocyte Migration Involved In Immune Response
Innate Immune Response-activating Signaling Pathway
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Protein Phosphorylation
Exocytosis
Phagocytosis
Response To Stress
Inflammatory Response
Cell Adhesion
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Integrin-mediated Signaling Pathway
Mesoderm Development
Positive Regulation Of Cell Population Proliferation
Regulation Of Cell Shape
Peptidyl-tyrosine Phosphorylation
Cytokine-mediated Signaling Pathway
Cell Differentiation
Positive Regulation Of Actin Filament Polymerization
Lipopolysaccharide-mediated Signaling Pathway
Regulation Of Actin Cytoskeleton Organization
Intracellular Signal Transduction
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Negative Regulation Of Apoptotic Process
Leukocyte Degranulation
Innate Immune Response
Respiratory Burst After Phagocytosis
Protein Autophosphorylation
Regulation Of Inflammatory Response
Regulation Of Phagocytosis
Defense Response To Gram-positive Bacterium
Leukocyte Migration
Regulation Of DNA-binding Transcription Factor Activity
Type II Interferon-mediated Signaling Pathway
Cellular Response To Lipid
Regulation Of Podosome Assembly
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Nef and signal transduction
FCGR activation
Regulation of signaling by CBL
Regulation of signaling by CBL
FCGR3A-mediated IL10 synthesis
FCGR3A-mediated phagocytosis
Signaling by CSF3 (G-CSF)
Signaling by CSF3 (G-CSF)
Signaling by CSF1 (M-CSF) in myeloid cells
Inactivation of CSF3 (G-CSF) signaling
Inactivation of CSF3 (G-CSF) signaling
FLT3 signaling through SRC family kinases
Drugs
Artenimol
1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
Phosphonotyrosine
Quercetin
Bosutinib
Fostamatinib
Diseases
GWAS
Adult body size (
32376654
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Inflammatory bowel disease (
23128233
)
Liver enzyme levels (alkaline phosphatase) (
33972514
)
Migraine (
27322543
)
Interacting Genes
15 interacting genes:
DUX4
ERCC6
FYN
HCK
LYN
MAPK6
OGT
PRKCA
PTEN
RAD21
SRC
SUMO2
TAB1
TBPL1
YES1
117 interacting genes:
ABL1
ABL2
ACTB
ADAM15
AGK
AGR2
APP
AR
ARRB1
ASAP1
BCAR1
BCR
BPIFA1
BTK
CBL
CCDC88B
CCR3
CD2AP
CHST15
CREBBP
CSF2RB
CSF3R
CSK
CTAG1A
CTAG1B
CYB5D2
CYSRT1
DNM2
DOK1
DOK2
EGFR
ELMO1
ERBB2
ERBB3
ERBB4
EVL
FASLG
FCGR1A
FCGR2A
FHL2
FHL5
GAB1
GOPC
GRB14
HNRNPK
HSF2BP
IL6ST
INCA1
INPP5D
IRF2BPL
KHDRBS1
KIT
KPRP
KRT31
KRT34
KRT35
KRT36
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP3-1
LCP2
LETMD1
LMNA
MAP4K5
MDK
MDM2
MET
MID2
MKRN3
MTUS2
NBPF19
NGEF
NOTCH2NLA
PAK2
PECAM1
PIK3CB
PIK3R1
PIK3R2
PLAUR
PLCG1
PLCG2
PLEKHG4
PNMA1
PRRG4
RAPGEF1
RASA1
RASA3
RBPMS
RPL10
SF3B3
SH2B2
SH3BP1
SH3KBP1
SKAP2
SOS1
SPRR2A
STAT3
TEKT4
TEPSIN
TNK2
TOX2
TP73
TRIM27
TRIP6
TRPV4
TSG101
UNC119
VAV1
WAS
WDCP
WIPF1
WNT2
ZSCAN4
Entrez ID
6134
3055
HPRD ID
02421
00796
Ensembl ID
ENSG00000147403
ENSG00000101336
Uniprot IDs
P27635
X5D2T3
A8K4G3
P08631
PDB IDs
2PA2
5AJ0
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6W6L
7F5S
7XNX
7XNY
8A3D
8FLD
8FLE
8FLF
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8K2C
8QFD
8XSY
8XSZ
8YOO
8YOP
9C3H
9GMO
1AD5
1BU1
1QCF
2C0I
2C0O
2C0T
2HCK
2HK5
2OI3
2OJ2
3HCK
3NHN
3RBB
3REA
3REB
3VRY
3VRZ
3VS0
3VS1
3VS2
3VS3
3VS4
3VS5
3VS6
3VS7
4HCK
4LUD
4LUE
4ORZ
4U5W
5H09
5H0B
5H0E
5H0G
5H0H
5HCK
5NUH
5ZJ6
8F2P
9BYJ
Enriched GO Terms of Interacting Partners
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Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Fc-gamma Receptor Signaling Pathway
Non-membrane Spanning Protein Tyrosine Kinase Activity
Fc Receptor Signaling Pathway
Protein Modification Process
T Cell Costimulation
Protein Tyrosine Kinase Activity
Ephrin Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Protein Kinase Activity
Protein Phosphorylation
Innate Immune Response-activating Signaling Pathway
Negative Regulation Of Inflammatory Response
Immune Response-activating Signaling Pathway
Intracellular Signal Transduction
Kinase Activity
Stimulatory C-type Lectin Receptor Signaling Pathway
Phosphate-containing Compound Metabolic Process
Phosphorylation
Cellular Response To Lectin
Signaling Receptor Binding
Cellular Response To Platelet-derived Growth Factor Stimulus
Enzyme Binding
Activation Of Innate Immune Response
Actin Filament
Negative Regulation Of Immune Response
Immune Response-regulating Signaling Pathway
Response To Platelet-derived Growth Factor
Activation Of Immune Response
Leukocyte Migration
Ephrin Receptor Binding
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Cell Cycle Process
Negative Regulation Of Defense Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Defense Response
Protein Metabolic Process
Transferase Activity
Positive Regulation Of Innate Immune Response
Response To Peptide Hormone
Transmembrane Transporter Binding
Regulation Of Phosphorus Metabolic Process
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Cell Cycle
Response To Reactive Oxygen Species
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Surface Receptor Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
SH3 Domain Binding
Signal Transduction
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Intracellular Signal Transduction
Regulation Of Endocytosis
Intracellular Signaling Cassette
Cytosol
Immune System Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Supramolecular Fiber Organization
Regulation Of Programmed Cell Death
Regulation Of Intracellular Signal Transduction
Keratin Filament
Immune Response-regulating Signaling Pathway
Protein Tyrosine Kinase Activity
ERBB Signaling Pathway
Fc Receptor Signaling Pathway
Regulation Of Cellular Component Organization
Positive Regulation Of Immune System Process
Protein Binding
Regulation Of Signal Transduction
Antigen Receptor-mediated Signaling Pathway
Phosphotyrosine Residue Binding
Intermediate Filament
Regulation Of Immune System Process
Plasma Membrane
Regulation Of Apoptotic Process
Regulation Of Small GTPase Mediated Signal Transduction
Immune Response-activating Signaling Pathway
T Cell Receptor Signaling Pathway
Regulation Of Vesicle-mediated Transport
Negative Regulation Of Programmed Cell Death
Cell-cell Junction
Developmental Process
Regulation Of Cell Motility
Regulation Of Immune Response
Actin Filament Organization
Activation Of Immune Response
Regulation Of Cell Communication
Regulation Of Signaling
Response To Growth Factor
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Regulation Of Locomotion
Identical Protein Binding
Endocytosis
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Tagcloud (Intersection)
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