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RNH1 and ANG
Number of citations of the paper that reports this interaction (PubMedID
9311977
)
50
Data Source:
HPRD
(in vitro)
RNH1
ANG
Description
ribonuclease/angiogenin inhibitor 1
angiogenin
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Lamellipodium
Angiogenin-PRI Complex
Extracellular Exosome
Extracellular Region
Basement Membrane
Extracellular Space
Nucleus
Chromosome
Nucleolus
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Actin Cytoskeleton
Endocytic Vesicle
Growth Cone
Angiogenin-PRI Complex
Neuronal Cell Body
Molecular Function
Protein Binding
Ribonuclease Inhibitor Activity
Nucleic Acid Binding
DNA Binding
Actin Binding
Nuclease Activity
Endonuclease Activity
RNA Endonuclease Activity
RNA Nuclease Activity
TRNA-specific Ribonuclease Activity
Signaling Receptor Binding
Copper Ion Binding
Protein Binding
Heparin Binding
Hydrolase Activity
RRNA Binding
Peptide Binding
Protein Homodimerization Activity
Ribosome Binding
Receptor Ligand Activity
Biological Process
Cytoplasmic Translation
MRNA Catabolic Process
Cell Migration
Negative Regulation Of Translation In Response To Stress
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
TRNA Stabilization
Regulation Of Angiogenesis
Angiogenesis
Ovarian Follicle Development
Oocyte Maturation
Response To Hypoxia
Response To Yeast
Placenta Development
Positive Regulation Of Endothelial Cell Proliferation
Cytoplasmic Translation
Receptor-mediated Endocytosis
Cell Communication
Signal Transduction
RRNA Transcription
Response To Hormone
TRNA Decay
Cell Migration
Negative Regulation Of Translation
Antibacterial Humoral Response
Antifungal Humoral Response
Signaling
Actin Filament Polymerization
Cell Differentiation
Negative Regulation Of Translation In Response To Stress
Cellular Response To Stress
Stress Granule Assembly
TRNA Stabilization
Positive Regulation Of Phosphorylation
Homeostatic Process
Negative Regulation Of Apoptotic Process
Innate Immune Response
Negative Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Protein Secretion
Defense Response To Gram-positive Bacterium
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Hematopoietic Stem Cell Proliferation
Pathways
Adherens junctions interactions
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis
Drugs
Diseases
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS
Body mass index (
25673413
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Blood protein levels (
30072576
)
Interacting Genes
5 interacting genes:
ANG
CEBPA
OGT
RNASE1
SDCBP
8 interacting genes:
ABCG8
ACTC1
ACTN2
ATP6AP1
CRIPTO
PTEN
RNH1
TNFSF8
Entrez ID
6050
283
HPRD ID
01412
00105
Ensembl ID
ENSG00000023191
ENSG00000214274
Uniprot IDs
A0A140VJT8
P13489
P03950
W0UV28
PDB IDs
1A4Y
1Z7X
2BEX
2Q4G
1A4Y
1ANG
1AWZ
1B1E
1B1I
1B1J
1GV7
1H0D
1H52
1H53
1HBY
1K58
1K59
1K5A
1K5B
1UN3
1UN4
1UN5
2ANG
4AHD
4AHE
4AHF
4AHG
4AHH
4AHI
4AHJ
4AHK
4AHL
4AHM
4AHN
4AOH
4B36
5EOP
5EPZ
5EQO
5M9A
5M9C
5M9G
5M9J
5M9M
5M9P
5M9Q
5M9R
5M9S
5M9T
5M9V
7NPM
7PNJ
7PNP
7PNR
8AF0
9BDL
9BDN
9BDP
Enriched GO Terms of Interacting Partners
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Peptide Binding
Hematopoietic Stem Cell Proliferation
RNA Nuclease Activity
Organelle Organization
Negative Regulation Of RNA Metabolic Process
Defense Response To Gram-positive Bacterium
Endonuclease Activity
Defense Response
Regulation Of Phosphorus Metabolic Process
Cell Communication
Stem Cell Proliferation
Response To Stress
TRNA-specific Ribonuclease Activity
Protein-containing Complex Organization
Angiogenin-PRI Complex
Nuclease Activity
Macromolecule Biosynthetic Process
Protein-containing Complex Assembly
Animal Organ Development
Cytoplasmic Translation
Signaling
Cellular Component Assembly
Response To Hormone
Cell Maturation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Chromatin DNA Binding
CHOP-C/EBP Complex
Regulation Of Ubiquitin-dependent Protein Catabolic Process
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Response To Nutrient
Response To Vitamin B2
White Fat Cell Proliferation
Memory
C/EBP Complex
Negative Regulation Of Hematopoietic Stem Cell Proliferation
Rb-E2F Complex
Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery
Telomere Tethering At Nuclear Periphery
Nuclear Pore Cytoplasmic Filaments
Ribonuclease A Activity
Ribonucleoside-diphosphate Reductase Complex
Positive Regulation Of G0 To G1 Transition
Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor
Purine Nucleotide Binding
Ribonucleoside-diphosphate Reductase Activity
Interleukin-5 Receptor Binding
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Interleukin-5 Receptor Complex
Positive Regulation Of Extracellular Exosome Assembly
Regulation Of Extracellular Exosome Assembly
Filopodium
Sarcomere
Synapse
Actin Filament
Titin Z Domain Binding
Actin Filament Uncapping
Plasma Membrane
Apical Plasma Membrane
Negative Regulation Of Synaptic Vesicle Clustering
Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity
Negative Regulation Of Keratinocyte Migration
Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity
Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity
Angiogenin-PRI Complex
Negative Regulation Of Intestinal Cholesterol Absorption
Negative Regulation Of Intestinal Phytosterol Absorption
Actomyosin Structure Organization
Phospholipase C-activating Angiotensin-activated Signaling Pathway
Central Nervous System Myelin Maintenance
Rhythmic Synaptic Transmission
Ribonuclease Inhibitor Activity
Nodal Binding
Negative Regulation Of Intestinal Absorption
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