RNH1 and NUP98

		RNH1	NUP98
Description		ribonuclease/angiogenin inhibitor 1	nucleoporin 98 and 96 precursor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Angiogenin-PRI Complex Extracellular Exosome	Kinetochore Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Membrane Nuclear Body Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Nuclear Pore Cytoplasmic Filaments Nuclear Pore Nuclear Basket Ribonucleoprotein Complex
	Molecular Function	Protein Binding Ribonuclease Inhibitor Activity	Transcription Coactivator Activity RNA Binding MRNA Binding Protein Binding Nuclear Localization Sequence Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity Structural Constituent Of Nuclear Pore Peptide Binding Molecular Condensate Scaffold Activity Promoter-specific Chromatin Binding
	Biological Process	Cytoplasmic Translation MRNA Catabolic Process Cell Migration Negative Regulation Of Translation In Response To Stress Regulation Of Arp2/3 Complex-mediated Actin Nucleation TRNA Stabilization Regulation Of Angiogenesis	Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery RNA Export From Nucleus Proteolysis Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Pore Organization Protein Transport Telomere Tethering At Nuclear Periphery Positive Regulation Of DNA-templated Transcription Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Transport Nuclear Pore Complex Assembly
Pathways
Drugs
Diseases
GWAS		Body mass index ( 25673413) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494)	Malaria ( 31844061) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736)
Interacting Genes		5 interacting genes: ANG CEBPA OGT RNASE1 SDCBP	19 interacting genes: APC CREBBP CSNK2A1 EP300 HDAC1 IPO5 KPNB1 NUP133 NUP188 NUP205 NUP62 NUP88 NXF1 RAE1 RCC1 SEC13 TNPO1 TNPO2 TPR
Entrez ID		6050	4928
HPRD ID		01412	03012
Ensembl ID		ENSG00000023191	ENSG00000110713
Uniprot IDs		A0A140VJT8 P13489	A0A8V8TR21 H0YCR0 H0YEN4 P52948
PDB IDs		1A4Y 1Z7X 2BEX 2Q4G	1KO6 2Q5X 2Q5Y 3MMY 4OWR 5A9Q 6BZM 7F60 7F90 7MNI 7PEQ 7Q64 7Q65 7Q66 7Q67 7VPG 7VPH 8CI8
Enriched GO Terms of Interacting Partners?		Peptide Binding Hematopoietic Stem Cell Proliferation RNA Nuclease Activity Organelle Organization Negative Regulation Of RNA Metabolic Process Defense Response To Gram-positive Bacterium Endonuclease Activity Defense Response Regulation Of Phosphorus Metabolic Process Cell Communication Stem Cell Proliferation Response To Stress TRNA-specific Ribonuclease Activity Protein-containing Complex Organization Angiogenin-PRI Complex Nuclease Activity Macromolecule Biosynthetic Process Protein-containing Complex Assembly Animal Organ Development Cytoplasmic Translation Signaling Cellular Component Assembly Response To Hormone Cell Maturation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromatin DNA Binding CHOP-C/EBP Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Nutrient Response To Vitamin B2 White Fat Cell Proliferation Memory C/EBP Complex Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Telomere Tethering At Nuclear Periphery Nuclear Pore Cytoplasmic Filaments Ribonuclease A Activity Ribonucleoside-diphosphate Reductase Complex Positive Regulation Of G0 To G1 Transition Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Purine Nucleotide Binding Ribonucleoside-diphosphate Reductase Activity Interleukin-5 Receptor Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Interleukin-5 Receptor Complex Positive Regulation Of Extracellular Exosome Assembly Regulation Of Extracellular Exosome Assembly	Nuclear Pore Nuclear Transport Nucleocytoplasmic Transport Protein Import Into Nucleus Import Into Nucleus Nuclear Envelope RNA Transport Structural Constituent Of Nuclear Pore Protein Localization To Nucleus MRNA Transport Nucleobase-containing Compound Transport Establishment Of Protein Localization To Organelle RNA Export From Nucleus Protein Localization To Organelle Intracellular Transport Nuclear Export Intracellular Protein Transport Protein Transport Nuclear Localization Sequence Binding Cellular Localization Establishment Of Protein Localization Establishment Of Localization In Cell MRNA Export From Nucleus Intracellular Protein Localization Regulation Of Mitotic Spindle Organization Nuclear Import Signal Receptor Activity Regulation Of Microtubule Cytoskeleton Organization Nucleoplasm Cytosol Nuclear Pore Organization Histone H3K27 Acetyltransferase Activity Regulation Of Cytoskeleton Organization Nucleus Regulation Of Microtubule-based Process Nuclear Membrane Regulation Of Mitotic Spindle Assembly Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Nuclear Pore Inner Ring Small GTPase Binding Regulation Of Cell Cycle Kinetochore Ribosomal Protein Import Into Nucleus RNA Import Into Nucleus Nucleus Organization Regulation Of Spindle Assembly Positive Regulation Of Protein Localization To Nucleus Regulation Of Cell Cycle Process Positive Regulation Of Protein Import Into Nucleus
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