ANG and RNH1

Number of citations of the paper that reports this interaction (PMID 9311977)
41

Data Source:
HPRD (in vitro)

		ANG	RNH1
Gene Name		angiogenin, ribonuclease, RNase A family, 5	ribonuclease/angiogenin inhibitor 1
Image
Gene Ontology Annotations	Cellular Component	Basal Lamina Extracellular Space Nucleus Nucleolus Growth Cone Angiogenin-PRI Complex Neuronal Cell Body Extracellular Vesicular Exosome	Cytoplasm Angiogenin-PRI Complex Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Actin Binding Endonuclease Activity Ribonuclease Activity Receptor Binding Copper Ion Binding Protein Binding Heparin Binding RRNA Binding Peptide Binding	Protein Binding Ribonuclease Inhibitor Activity
	Biological Process	Angiogenesis Ovarian Follicle Development Oocyte Maturation Response To Hypoxia Placenta Development Positive Regulation Of Endothelial Cell Proliferation Diacylglycerol Biosynthetic Process Cell Communication Activation Of Phospholipase C Activity RRNA Transcription Response To Hormone Cell Migration Negative Regulation Of Translation Actin Filament Polymerization Activation Of Protein Kinase B Activity Activation Of Phospholipase A2 Activity Positive Regulation Of Phosphorylation Homeostatic Process Negative Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Protein Secretion Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis	MRNA Catabolic Process Negative Regulation Of Catalytic Activity Regulation Of Angiogenesis
Pathways
Drugs		Pyrophosphate 2- Pyroglutamic Acid Citric Acid
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ABCG8 ACTC1 ACTN2 ATP6AP1 PTEN RNH1 TDGF1 TNFSF8	3 interactors: ANG RNASE1 SDCBP
Entrez ID		283	6050
HPRD ID		00105	01412
Ensembl ID		ENSG00000214274	ENSG00000023191
Uniprot IDs		P03950	P13489
PDB IDs		1A4Y 1ANG 1AWZ 1B1E 1B1I 1B1J 1GV7 1H0D 1H52 1H53 1HBY 1K58 1K59 1K5A 1K5B 1UN3 1UN4 1UN5 2ANG 4AHD 4AHE 4AHF 4AHG 4AHH 4AHI 4AHJ 4AHK 4AHL 4AHM 4AHN 4AOH 4B36	1A4Y 1Z7X 2BEX 2Q4G
Enriched GO Terms of Interacting Partners?		Cardiac Muscle Tissue Development Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Striated Muscle Tissue Development Muscle Tissue Development Actin Filament-based Movement Negative Regulation Of Transport Endothelial Cell Migration Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Epithelial Cell Migration Epithelium Migration Response To Drug Heart Development Cardiac Muscle Cell Differentiation Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Activation Of APC-Cdc20 Complex Activity Postsynaptic Density Assembly Negative Regulation Of Presynaptic Membrane Organization Regulation Of Cell-matrix Adhesion Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Cardiocyte Differentiation Response To Ethanol Negative Regulation Of Dendritic Spine Morphogenesis Regulation Of Cell Death Negative Regulation Of Ribosome Biogenesis Central Nervous System Myelin Maintenance Positive Regulation Of Osteoclast Development Ameboidal-type Cell Migration Regulation Of Presynaptic Membrane Organization Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Cell-substrate Adhesion Negative Regulation Of Dendritic Spine Development Microspike Assembly Rhythmic Synaptic Transmission Skeletal Muscle Thin Filament Assembly Activation Of Anaphase-promoting Complex Activity Synapse Maturation Muscle Contraction Response To Nutrient Cardiovascular System Development Striated Muscle Cell Differentiation Positive Regulation Of Mitotic Metaphase/anaphase Transition Intestinal Cholesterol Absorption Male Mating Behavior	RNA Phosphodiester Bond Hydrolysis Diacylglycerol Biosynthetic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Activation Of Phospholipase A2 Activity Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Secretion Positive Regulation Of Phospholipase A2 Activity Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Substrate-dependent Cell Migration, Cell Extension Regulation Of Phospholipase A2 Activity Actin Cytoskeleton Organization Regulation Of Secretion Actin Filament-based Process Diacylglycerol Metabolic Process Positive Regulation Of Transport RRNA Transcription Oocyte Maturation Positive Regulation Of Organelle Assembly Activation Of Protein Kinase B Activity Cell Migration Positive Regulation Of Phosphorylation Cell Motility Substrate-dependent Cell Migration Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Cellular Localization Actin Filament Polymerization Oocyte Development Oocyte Differentiation Activation Of Phospholipase C Activity Cytoskeleton Organization Positive Regulation Of Phospholipase C Activity Positive Regulation Of Exocytosis Positive Regulation Of Endothelial Cell Proliferation Locomotion Ovarian Follicle Development Regulation Of Phosphorylation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Tagcloud ?		ace angiotensin b2 bk blockade blocker cbf circulation contributions converting dogs doppler enalaprilat icatibant intake intrarenal kallikrein kinin maintained mbf medullary micergrams micrograms needle probes renin salt upregulates vasodilatory
Tagcloud (Difference) ?		ace angiotensin b2 bk blockade blocker cbf circulation contributions converting dogs doppler enalaprilat icatibant intake intrarenal kallikrein kinin maintained mbf medullary micergrams micrograms needle probes renin salt upregulates vasodilatory
Tagcloud (Intersection) ?