RNH1

Description		ribonuclease/angiogenin inhibitor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Angiogenin-PRI Complex Extracellular Exosome
	Molecular Function	Protein Binding Ribonuclease Inhibitor Activity
	Biological Process	Cytoplasmic Translation MRNA Catabolic Process Cell Migration Negative Regulation Of Translation In Response To Stress Regulation Of Arp2/3 Complex-mediated Actin Nucleation TRNA Stabilization Regulation Of Angiogenesis
Pathways
Drugs
Diseases
GWAS		Body mass index ( 25673413) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494)
Novel Interacting Genes		3 novel interacting genes: NUP98 RRM1 TH
Interacting Genes		5 interacting genes: ANG CEBPA OGT RNASE1 SDCBP
Entrez ID		6050
HPRD ID		01412
Ensembl ID		ENSG00000023191
Uniprot IDs		A0A140VJT8 P13489
PDB IDs		1A4Y 1Z7X 2BEX 2Q4G
Enriched GO Terms of Interacting Partners?		Peptide Binding Hematopoietic Stem Cell Proliferation RNA Nuclease Activity Organelle Organization Negative Regulation Of RNA Metabolic Process Defense Response To Gram-positive Bacterium Endonuclease Activity Defense Response Regulation Of Phosphorus Metabolic Process Cell Communication Stem Cell Proliferation Response To Stress TRNA-specific Ribonuclease Activity Protein-containing Complex Organization Angiogenin-PRI Complex Nuclease Activity Macromolecule Biosynthetic Process Protein-containing Complex Assembly Animal Organ Development Cytoplasmic Translation Signaling Cellular Component Assembly Response To Hormone Cell Maturation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromatin DNA Binding CHOP-C/EBP Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Nutrient Response To Vitamin B2 White Fat Cell Proliferation Memory C/EBP Complex Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Telomere Tethering At Nuclear Periphery Nuclear Pore Cytoplasmic Filaments Ribonuclease A Activity Ribonucleoside-diphosphate Reductase Complex Positive Regulation Of G0 To G1 Transition Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Purine Nucleotide Binding Ribonucleoside-diphosphate Reductase Activity Interleukin-5 Receptor Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Interleukin-5 Receptor Complex Positive Regulation Of Extracellular Exosome Assembly Regulation Of Extracellular Exosome Assembly
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