RNF4 and PATZ1

Number of citations of the paper that reports this interaction (PMID 10713105)
16

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		RNF4	PATZ1
Gene Name		ring finger protein 4	POZ (BTB) and AT hook containing zinc finger 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm PML Body	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Ligase Activity Nucleosome Binding SUMO Polymer Binding Identical Protein Binding Androgen Receptor Binding	DNA Binding Chromatin Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Androgen Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Arsenic-containing Substance Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination Regulation Of Spindle Assembly Regulation Of Kinetochore Assembly	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis Male Gonad Development T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		37 interactors: AR ATXN1 ESR1 GSC2 HIST2H3C HMGA1 HNF4A IKBKG MECP2 PATZ1 PGR PML SKIL SP1 SRPK2 SUMO1 SUMO2 TBP TCF20 TRAIP TRIM28 TRPS1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L6 UBE2T UBE2W UEVLD	6 interactors: BACH1 BACH2 MITF PRKAR1A RNF4 TP53
Entrez ID		6047	23598
HPRD ID		04167	05522
Ensembl ID		ENSG00000063978	ENSG00000100105
Uniprot IDs		P78317	Q9HBE1
PDB IDs		2EA6 2XEU	2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein Ubiquitination Transcription Initiation From RNA Polymerase II Promoter Protein K11-linked Ubiquitination DNA-templated Transcription, Initiation Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Protein Modification Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Modification-dependent Protein Catabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Protein Catabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Heterocycle Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Aromatic Compound Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Cellular Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway ISG15-protein Conjugation	Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Oxygen Levels Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Macromitophagy Regulation Of Kinetochore Assembly Oligodendrocyte Apoptotic Process Double-strand Break Repair DNA Damage Checkpoint Negative Regulation Of Helicase Activity Regulation Of Centromere Complex Assembly Gastrulation Regulation Of Metabolic Process Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Chromosome Organization Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Mitochondrial DNA Repair
Tagcloud ?		barrier begins calculations catalyzed conjugating d117 deprotonation dimeric e3 elusive employing gets guiding kcal ligase ligases md mechanics nucleophilic oxyanion qm ring sumo2 thioester transfer ub ubch5a ubiquitylation universal	anaplastic anchorage behaviors carcinogenesis carcinomas cytoplasm debated dedifferentiated delocalized differentiated ectopic emerging fact finger histotype increasingly insights invasiveness inverse mesenchymal oncogene opposing papillary poz proceeding restoration suppressor thyroid undifferentiated
Tagcloud (Difference) ?		barrier begins calculations catalyzed conjugating d117 deprotonation dimeric e3 elusive employing gets guiding kcal ligase ligases md mechanics nucleophilic oxyanion qm ring sumo2 thioester transfer ub ubch5a ubiquitylation universal	anaplastic anchorage behaviors carcinogenesis carcinomas cytoplasm debated dedifferentiated delocalized differentiated ectopic emerging fact finger histotype increasingly insights invasiveness inverse mesenchymal oncogene opposing papillary poz proceeding restoration suppressor thyroid undifferentiated
Tagcloud (Intersection) ?