PATZ1 and KRT33B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PATZ1	KRT33B
Description		POZ/BTB and AT hook containing zinc finger 1	keratin 33B
Image			No pdb structure
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Nucleoplasm	Extracellular Space Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Metal Ion Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Regulation Of DNA-templated Transcription Spermatogenesis Male Gonad Development Regulation Of Gene Expression Negative Regulation Of Endothelial Cell Migration T Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Cycle Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) Fish- and plant-related diet ( 32066663) Height ( 31562340) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red cell distribution width ( 28957414) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)
Interacting Genes		81 interacting genes: ACTMAP AKAP8L BACH1 BACH2 BOLL BPIFA1 CEP76 CFAP68 CLK1 CPSF7 CYSRT1 DAZAP2 DVL3 EYA2 FAM168A FAM168B GOLGA6L9 GPANK1 HNRNPF HNRNPH1 HSPB2 HSPB2-C11orf52 HYI IQUB KLF1 KLHDC7B KRT33B KRTAP12-2 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 LMO2 LONRF1 LURAP1L LZTS2 MDFI MITF MSX2 NFKBID NHLRC4 OIP5 PFDN5 PHF1 PPP1R16B PPP1R37 PRDM14 PRDM6 PRKAR1A PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM10 RBPMS RBPMS2 RFX6 RIPPLY1 RNF4 SLAIN1 SMYD1 SPAG8 TLE5 TNS2 TRAF1 TRIP6 TSC1 WWOX WWP2 ZBTB32 ZIC1 ZIM2	61 interacting genes: ABI2 AIMP2 AQP1 ARFIP1 ATG9A C1orf216 CCDC24 CNNM3 COX5B CYSRT1 DES DTNB DUSP21 FASLG FRS3 GOLGA6L2 GSTP1 HAPLN2 HDAC4 HGS HOXA1 INCA1 KDM1A KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LMO4 MOS NUP54 NUP58 PATZ1 PPP1R18 RAB26 RAMAC RTP5 RUNX1T1 SCNM1 SGF29 SHC3 USP2 VPS37C
Entrez ID		23598	3884
HPRD ID		05522	04136
Ensembl ID		ENSG00000100105	ENSG00000131738
Uniprot IDs		Q9HBE1	Q14525
PDB IDs		2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Splicing	Intermediate Filament Organization Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Protein Binding Epidermis Development Intermediate Filament Cytoskeleton Extracellular Exosome Cornified Envelope Tissue Development Developmental Process Structural Constituent Of Cytoskeleton
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