MYG1 and CPLX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYG1	CPLX2
Description		MYG1 exonuclease	complexin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleus Cytoplasm Cytosol Dendrite SNARE Complex Cell Projection Neuronal Cell Body Terminal Bouton Perikaryon Calyx Of Held Synapse Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	3'-5'-RNA Exonuclease Activity Nuclease Activity Protein Binding Hydrolase Activity	SNARE Binding Protein Binding Syntaxin-1 Binding Syntaxin Binding Calcium-dependent Protein Binding
	Biological Process	Mitochondrial RNA Metabolic Process RRNA Processing MRNA Processing Locomotory Exploration Behavior	Neurotransmitter Transport Exocytosis Vesicle Docking Involved In Exocytosis Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Exocytosis Cell Differentiation Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Synaptic Plasticity Mast Cell Degranulation Modulation Of Chemical Synaptic Transmission
Pathways
Drugs
Diseases
GWAS			Age-related nuclear cataracts ( 24951543) Chronotype ( 30696823) Obesity-related traits ( 23251661)
Interacting Genes		38 interacting genes: AGTRAP ALDH7A1 AP1B1 APOA5 ARL6IP1 BSND CDS2 CMTM5 COPS5 CPLX2 CTSA DDIT4L DESI2 DGAT2L6 FAM9B GADD45GIP1 GRB2 HORMAD1 HSPB1 MAN1C1 METTL9 NDN PLIN3 RHBDD2 RXRB SFT2D1 SKIL SLC17A9 SPG21 SUMO2 SYNGR1 SYP TLCD4 TMEM229B TMEM239 TNMD WWOX YIF1A	7 interacting genes: APP MYG1 NDRG4 PBX3 STX2 STX3 TSFM
Entrez ID		60314	10814
HPRD ID		10705	09234
Ensembl ID		ENSG00000139637	ENSG00000145920
Uniprot IDs		Q9HB07	Q6PUV4
PDB IDs
Enriched GO Terms of Interacting Partners?			Vesicle Docking Membrane Docking Organelle Localization By Membrane Tethering Locomotory Behavior SNAP Receptor Activity SNARE Complex Amyloid-beta Complex Growth Cone Lamellipodium Visual Behavior Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Visual Learning SNARE Binding Posterior Compartment Specification Anterior Compartment Pattern Formation Adult Locomotory Behavior Acetylcholine Receptor Activator Activity Associative Learning Lipoprotein Particle Positive Regulation Of Protein Import Organelle Membrane Fusion Organelle Localization Vesicle Fusion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Organelle Fusion Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Chemotaxis Anatomical Structure Morphogenesis Adult Behavior Cellular Response To Norepinephrine Stimulus Growth Cone Positive Regulation Of Synaptic Transmission Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Membrane Fusion Compartment Pattern Specification Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation
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