MYG1 and ALDH7A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYG1	ALDH7A1
Description		MYG1 exonuclease	aldehyde dehydrogenase 7 family member A1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Extracellular Exosome
	Molecular Function	3'-5'-RNA Exonuclease Activity Nuclease Activity Protein Binding Hydrolase Activity	Aldehyde Dehydrogenase (NAD+) Activity L-aminoadipate-semialdehyde Dehydrogenase Activity Protein Binding Betaine-aldehyde Dehydrogenase (NAD+) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor Identical Protein Binding
	Biological Process	Mitochondrial RNA Metabolic Process RRNA Processing MRNA Processing Locomotory Exploration Behavior	Aldehyde Metabolic Process Sensory Perception Of Sound Glycine Betaine Biosynthetic Process From Choline Choline Catabolic Process
Pathways			Choline catabolism Lysine catabolism
Drugs			NADH Artenimol
Diseases
GWAS			Colorectal cancer ( 30529582) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Metabolite levels ( 23823483) Osteoporosis ( 20072603)
Interacting Genes		38 interacting genes: AGTRAP ALDH7A1 AP1B1 APOA5 ARL6IP1 BSND CDS2 CMTM5 COPS5 CPLX2 CTSA DDIT4L DESI2 DGAT2L6 FAM9B GADD45GIP1 GRB2 HORMAD1 HSPB1 MAN1C1 METTL9 NDN PLIN3 RHBDD2 RXRB SFT2D1 SKIL SLC17A9 SPG21 SUMO2 SYNGR1 SYP TLCD4 TMEM229B TMEM239 TNMD WWOX YIF1A	6 interacting genes: APP EPS8 LCN2 MYG1 OGT RECQL5
Entrez ID		60314	501
HPRD ID		10705	00124
Ensembl ID		ENSG00000139637	ENSG00000164904
Uniprot IDs		Q9HB07	P49419
PDB IDs			2J6L 4X0T 4X0U 4ZUK 4ZUL 4ZVW 4ZVX 4ZVY 6O4B 6O4C 6O4D 6O4E 6O4F 6O4G 6O4H 6O4I 6O4K 6O4L 6U2X 6V0Z
Enriched GO Terms of Interacting Partners?			Amyloid-beta Complex Response To Interleukin-1 Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Adult Locomotory Behavior Cellular Response To Oxygen-containing Compound Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Response To Nerve Growth Factor Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Response To Amyloid-beta Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Response To Amyloid-beta Positive Regulation Of Reactive Oxygen Species Metabolic Process Locomotory Behavior Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Hippocampal Neuron Apoptotic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Acetylcholine Receptor Activator Activity Response To Peptide Response To Cytokine Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Iron Ion Import Across Plasma Membrane Enterobactin Binding Positive Regulation Of Endothelial Tube Morphogenesis Iron Ion Sequestering Activity Positive Regulation Of Cold-induced Thermogenesis Mitotic DNA-templated DNA Replication PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Growth Cone Memory Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Protein-containing Complex Assembly Response To Monosaccharide Siderophore Transport Protein O-acetylglucosaminyltransferase Activity
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