MYG1 and HORMAD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYG1	HORMAD1
Description		MYG1 exonuclease	HORMA domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix	Condensed Nuclear Chromosome Synaptonemal Complex Nucleus Chromosome
	Molecular Function	3'-5'-RNA Exonuclease Activity Nuclease Activity Protein Binding Hydrolase Activity	Protein Binding
	Biological Process	Mitochondrial RNA Metabolic Process RRNA Processing MRNA Processing Locomotory Exploration Behavior	Blastocyst Development Homologous Chromosome Pairing At Meiosis Synaptonemal Complex Assembly Spermatogenesis Cell Differentiation Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Sister Chromatid Cohesion Meiotic Cell Cycle Meiotic Recombination Checkpoint Signaling Regulation Of Homologous Chromosome Segregation
Pathways
Drugs
Diseases
GWAS			Body mass index ( 26426971) Caffeine consumption from coffee ( 33287642) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 27863252 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) Rhegmatogenous retinal detachment ( 23585552) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		38 interacting genes: AGTRAP ALDH7A1 AP1B1 APOA5 ARL6IP1 BSND CDS2 CMTM5 COPS5 CPLX2 CTSA DDIT4L DESI2 DGAT2L6 FAM9B GADD45GIP1 GRB2 HORMAD1 HSPB1 MAN1C1 METTL9 NDN PLIN3 RHBDD2 RXRB SFT2D1 SKIL SLC17A9 SPG21 SUMO2 SYNGR1 SYP TLCD4 TMEM229B TMEM239 TNMD WWOX YIF1A	4 interacting genes: BRCA1 MEOX2 MSL1 MYG1
Entrez ID		60314	84072
HPRD ID		10705	11396
Ensembl ID		ENSG00000139637	ENSG00000143452
Uniprot IDs		Q9HB07	A0A140VKG9 Q86X24
PDB IDs			8J69
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Centrosome Duplication Negative Regulation Of Centriole Replication BRCA1-A Complex XY Body BRCA1-B Complex Histone H2AK127 Ubiquitin Ligase Activity Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Lateral Element Nuclear Ubiquitin Ligase Complex Cellular Response To Indole-3-methanol Positive Regulation Of RNA Biosynthetic Process BRCA1-C Complex Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Gamma-tubulin Ring Complex Ubiquitin-modified Histone Reader Activity Histone H2AK129 Ubiquitin Ligase Activity Positive Regulation Of DNA-templated Transcription Response To Indole-3-methanol DNA Strand Resection Involved In Replication Fork Processing BRCA1-BARD1 Complex DNA Repair Complex Random Inactivation Of X Chromosome Nuclear Speck Segment Specification Somite Development Somite Specification Locomotory Exploration Behavior MSL Complex RNA Polymerase Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Fatty Acid Biosynthetic Process
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