LRP2BP and PICK1

Number of citations of the paper that reports this interaction (PMID 12508107)
4

Data Source:
HPRD (two hybrid)

		LRP2BP	PICK1
Gene Name		LRP2 binding protein	protein interacting with PRKCA 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytoplasm Mitochondrion Golgi Apparatus Cytoskeleton Plasma Membrane Cell Junction Endocytic Vesicle Membrane Presynaptic Membrane Neuron Projection Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Neuronal Postsynaptic Density
	Molecular Function	Protein Binding	G-protein Coupled Receptor Binding Protein Kinase C Binding Receptor Binding Protein Binding Protein C-terminus Binding ATPase Activity Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding Actin Filament Binding Arp2/3 Complex Binding
	Biological Process		Positive Regulation Of Receptor Internalization Protein Phosphorylation Protein Targeting Retrograde Vesicle-mediated Transport, Golgi To ER Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Monoamine Transport Glial Cell Development Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Response To Decreased Oxygen Levels Cellular Response To Glucose Starvation DNA Methylation Involved In Embryo Development DNA Methylation Involved In Gamete Generation Receptor Clustering Neuronal Ion Channel Clustering Long Term Synaptic Depression Dendritic Spine Organization Dendritic Spine Maintenance
Pathways			Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BAI2 COPS3 LRP2 PICK1 RBM4 SNW1 TSC22D4	47 interactors: APTX AQP1 ARF1 ARF3 ASIC1 ASIC2 ATXN1L ATXN3 ATXN7 ATXN7L3 BTG2 CIC COIL CTNNB1 EFNB1 EFNB2 EHD2 EPHB2 ERBB2 ERBB2IP F11R FXN GFI1 GFI1B GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIP1 GRM3 GRM7 JAM3 LRP2BP MLLT4 PARK2 PRKCA PRKCG PRLHR PVRL2 PVRL4 SACS SLC6A3 UBQLN4 USP7
Entrez ID		55805	9463
HPRD ID		10911	16176
Ensembl ID		ENSG00000109771	ENSG00000100151
Uniprot IDs		Q9P2M1	B3KS52 Q9NRD5
PDB IDs			2GZV
Enriched GO Terms of Interacting Partners?		Response To Abiotic Stimulus Response To Light Stimulus Regulation Of MRNA Splicing, Via Spliceosome Response To Radiation Regulation Of MRNA Processing Regulation Of RNA Splicing Positive Regulation Of Vitamin D Receptor Signaling Pathway Response To Stimulus Signal Transduction Developmental Process Signaling Cell Communication IRES-dependent Translational Initiation Cap-independent Translational Initiation Regulation Of Gene Expression, Epigenetic Regulation Of Vitamin D Receptor Signaling Pathway Circadian Regulation Of Translation DNA Methylation Involved In Embryo Development Nervous System Development Negative Regulation Of Translation In Response To Stress Cullin Deneddylation Cellular Response To Stimulus Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Dendritic Spine Maintenance Cytoplasmic Translational Initiation Positive Regulation By Host Of Viral Transcription Protein Deneddylation Neuronal Ion Channel Clustering Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Vitamin D Metabolic Process Negative Regulation Of Actin Nucleation RNA Splicing Multicellular Organismal Development Cytoplasmic Translation Positive Regulation Of Histone H3-K4 Methylation Regulation Of Translation In Response To Stress Negative Regulation Of Gene Expression Long Term Synaptic Depression Negative Regulation Of Biosynthetic Process Anatomical Structure Development Positive Regulation Of Receptor Internalization Negative Regulation Of Translational Initiation Regulation Of Arp2/3 Complex-mediated Actin Nucleation MRNA Processing Dendritic Spine Organization Entrainment Of Circadian Clock By Photoperiod DNA Methylation Involved In Gamete Generation Regulation Of Histone H3-K4 Methylation Regulation Of Actin Nucleation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Cell-cell Signaling Synaptic Transmission Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Cellular Response To Stimulus Regulation Of Cellular Process Response To Stimulus Signaling Cell Communication Behavior Regulation Of Synaptic Transmission Single-organism Behavior Neurological System Process Negative Regulation Of Synaptic Transmission Regulation Of Synaptic Transmission, Glutamatergic Signal Transduction Adenylate Cyclase-inhibiting G-protein Coupled Glutamate Receptor Signaling Pathway Anatomical Structure Development Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Nervous System Development Negative Regulation Of Synaptic Transmission, Glutamatergic Cell Junction Assembly Developmental Process Ion Transport Cell-cell Junction Organization Ion Transmembrane Transport G-protein Coupled Glutamate Receptor Signaling Pathway Histone Deubiquitination Learning Or Memory Negative Regulation Of Adenylate Cyclase Activity Multicellular Organismal Development Regulation Of Body Fluid Levels Negative Regulation Of Lyase Activity Establishment Of Endothelial Barrier Cognition Response To External Stimulus System Development Regulation Of Signaling Adherens Junction Organization Multicellular Organismal Response To Stress Negative Regulation Of CAMP Biosynthetic Process Cellular Process Negative Regulation Of CAMP Metabolic Process Sensory Perception Of Sour Taste Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Death Negative Regulation Of Programmed Cell Death
Tagcloud ?			altering ampa calsyntenin clarified confirming coordinated deprivation elicited excitotoxic glua1 glun2a glun2b glun3a grip1 hippocampal insults ionotropic ischemia ogd profound proteome repression sapap2 snap submitted synaptic tarpgamma3 transcriptome vulnerability
Tagcloud (Difference) ?			altering ampa calsyntenin clarified confirming coordinated deprivation elicited excitotoxic glua1 glun2a glun2b glun3a grip1 hippocampal insults ionotropic ischemia ogd profound proteome repression sapap2 snap submitted synaptic tarpgamma3 transcriptome vulnerability
Tagcloud (Intersection) ?