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RARB and PNRC1
Number of citations of the paper that reports this interaction (PMID
15604093
)
36
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
RARB
PNRC1
Gene Name
retinoic acid receptor, beta
proline-rich nuclear receptor coactivator 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nucleus
Molecular Function
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
DNA Binding
Steroid Hormone Receptor Activity
Retinoic Acid Receptor Activity
Protein Binding
Drug Binding
Zinc Ion Binding
Protein Complex Binding
Retinoid X Receptor Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Ureteric Bud Development
Glandular Epithelial Cell Development
Outflow Tract Septum Morphogenesis
Retinal Pigment Epithelium Development
Growth Plate Cartilage Development
Transcription Initiation From RNA Polymerase II Promoter
Signal Transduction
Positive Regulation Of Cell Proliferation
Negative Regulation Of Cell Proliferation
Gene Expression
Striatum Development
Regulation Of Myelination
Negative Regulation Of Chondrocyte Differentiation
Embryonic Hindlimb Morphogenesis
Multicellular Organism Growth
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Embryonic Eye Morphogenesis
Retinoic Acid Receptor Signaling Pathway
Embryonic Digestive Tract Development
Ventricular Cardiac Muscle Cell Differentiation
Transmembrane Transport
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Pathways
Generic Transcription Pathway
Signaling by Retinoic Acid
Nuclear Receptor transcription pathway
Orphan transporters
Drugs
Adapalene
Acitretin
Alitretinoin
Tazarotene
Etretinate
TTNPB
Tamibarotene
Diseases
GWAS
Airflow obstruction (
22837378
)
Obesity (extreme) (
19553259
)
Pulmonary function (
21946350
)
Pulmonary function (interaction) (
23284291
)
Protein-Protein Interactions
19 interactors:
CCNH
CEBPA
CEBPB
EIF3I
GATA3
HR
MAP6
MEOX2
NCOA1
NCOA3
NCOR2
NR4A2
PNRC1
PRKD2
RXRA
RXRB
RXRG
SMAD2
SRC
12 interactors:
AR
ESR2
ESRRG
GRB2
HNF4A
HNF4G
MAPK8
NR5A2
RARB
RARG
RORA
RORB
Entrez ID
5915
10957
HPRD ID
07183
08412
Ensembl ID
ENSG00000077092
ENSG00000146278
Uniprot IDs
F1D8S6
P10826
Q5QHG3
Q12796
PDB IDs
1HRA
1XAP
4DM6
4DM8
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Response To Lipid
Regulation Of Gene Expression
Gene Expression
Regulation Of Transcription, DNA-templated
Response To Steroid Hormone
Regulation Of Nucleic Acid-templated Transcription
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
In Utero Embryonic Development
Macromolecule Biosynthetic Process
Cellular Response To Organic Substance
Chordate Embryonic Development
Intracellular Receptor Signaling Pathway
Embryo Development Ending In Birth Or Egg Hatching
RNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Initiation
Regulation Of Nitrogen Compound Metabolic Process
Response To Organic Cyclic Compound
Response To Hormone
Gland Development
Reproductive Structure Development
Reproductive System Development
Response To Organic Substance
Embryo Development
Biosynthetic Process
Placenta Development
System Development
Positive Regulation Of Metabolic Process
Tissue Development
Regulation Of Metabolic Process
Cellular Response To Organic Cyclic Compound
Organ Development
Nucleobase-containing Compound Metabolic Process
Developmental Process Involved In Reproduction
Epithelium Development
Multicellular Organismal Development
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Steroid Hormone Mediated Signaling Pathway
Hormone-mediated Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Intracellular Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Cellular Response To Lipid
Cellular Response To Hormone Stimulus
Cellular Response To Organic Cyclic Compound
Response To Steroid Hormone
Response To Lipid
Response To Hormone
Cellular Response To Organic Substance
Transcription From RNA Polymerase II Promoter
Response To Organic Cyclic Compound
Response To Organic Substance
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
RNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Signal Transduction
Signaling
Cell Communication
Organ Development
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Gene Expression
Cellular Response To Stimulus
Retinoic Acid Receptor Signaling Pathway
Regulation Of Gene Expression
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
System Development
Endocrine Pancreas Development
Response To Stimulus
Nucleobase-containing Compound Metabolic Process
Retinal Pigment Epithelium Development
Multicellular Organismal Development
Prostate Gland Development
Tagcloud
?
activating
backcross
chromosomes
contain
cosegregated
enhancers
fragment
homology
interspecific
loci
mapped
mchr
mediate
none
rara
rarg
reports
responsive
restriction
retinoic
retinoid
rflvs
rxr
subclass
syntenic
terms
trans
variants
Tagcloud (Difference)
?
activating
backcross
chromosomes
contain
cosegregated
enhancers
fragment
homology
interspecific
loci
mapped
mchr
mediate
none
rara
rarg
reports
responsive
restriction
retinoic
retinoid
rflvs
rxr
subclass
syntenic
terms
trans
variants
Tagcloud (Intersection)
?