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PNRC1 and NR5A2
Number of citations of the paper that reports this interaction (PMID
15604093
)
36
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PNRC1
NR5A2
Gene Name
proline-rich nuclear receptor coactivator 1
nuclear receptor subfamily 5, group A, member 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Protein Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Phospholipid Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Bile Acid Metabolic Process
Embryo Development
Gene Expression
Intracellular Receptor Signaling Pathway
Endocrine Pancreas Development
Regulation Of Cell Proliferation
Homeostatic Process
Cholesterol Homeostasis
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Viral Genome Replication
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Pancreatic cancer (
20101243
)
Protein-Protein Interactions
12 interactors:
AR
ESR2
ESRRG
GRB2
HNF4A
HNF4G
MAPK8
NR5A2
RARB
RARG
RORA
RORB
19 interactors:
ALB
BCKDK
COPS5
EDF1
FTH1
NCOA1
NCOA3
NPPA
NR0B2
NRIP1
NSD1
PNRC1
PNRC2
POLR2D
PROX1
RAD54L2
SMARCD3
SRC
UBE2I
Entrez ID
10957
2494
HPRD ID
08412
06830
Ensembl ID
ENSG00000146278
ENSG00000116833
Uniprot IDs
Q12796
B4E2P3
F1D8R9
O00482
PDB IDs
1YOK
1YUC
1ZDU
2A66
3PLZ
3TX7
4DOR
4DOS
4IS8
Enriched GO Terms of Interacting Partners
?
Steroid Hormone Mediated Signaling Pathway
Hormone-mediated Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Intracellular Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Cellular Response To Lipid
Cellular Response To Hormone Stimulus
Cellular Response To Organic Cyclic Compound
Response To Steroid Hormone
Response To Lipid
Response To Hormone
Cellular Response To Organic Substance
Transcription From RNA Polymerase II Promoter
Response To Organic Cyclic Compound
Response To Organic Substance
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
RNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Signal Transduction
Signaling
Cell Communication
Organ Development
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Gene Expression
Cellular Response To Stimulus
Retinoic Acid Receptor Signaling Pathway
Regulation Of Gene Expression
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
System Development
Endocrine Pancreas Development
Response To Stimulus
Nucleobase-containing Compound Metabolic Process
Retinal Pigment Epithelium Development
Multicellular Organismal Development
Prostate Gland Development
Transcription, DNA-templated
RNA Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Intracellular Steroid Hormone Receptor Signaling Pathway
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Positive Regulation Of Metabolic Process
Regulation Of Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Androgen Receptor Signaling Pathway
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Intracellular Receptor Signaling Pathway
Regulation Of Metabolic Process
Cellular Metabolic Process
Metabolic Process
Regulation Of Cellular Process
Transcription From RNA Polymerase II Promoter
Peptidyl-lysine Modification
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Transcription, DNA-templated
Labyrinthine Layer Morphogenesis
Positive Regulation Of Organelle Assembly
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Embryonic Placenta Morphogenesis
Gland Morphogenesis
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Response To Nutrient Levels
Mammary Gland Development
Anatomical Structure Development
Negative Regulation Of Gene Expression
Response To Extracellular Stimulus
Negative Regulation Of Biosynthetic Process
Tagcloud
?
4f
6f
boosts
copyright
dn
endogenously
epiblast
episcs
feeder
impedes
ipscs
klf4
lrh1
mef
mefs
n2b27
oct4
pluripotency
pluripotent
primed
rarg
reprogram
reprogramming
reprograms
reserved
rights
sox2
supplementing
synthesised
Tagcloud (Difference)
?
4f
6f
boosts
copyright
dn
endogenously
epiblast
episcs
feeder
impedes
ipscs
klf4
lrh1
mef
mefs
n2b27
oct4
pluripotency
pluripotent
primed
rarg
reprogram
reprogramming
reprograms
reserved
rights
sox2
supplementing
synthesised
Tagcloud (Intersection)
?