PNRC1 and HNF4G

Number of citations of the paper that reports this interaction (PMID 15604093)
36

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PNRC1	HNF4G
Gene Name		proline-rich nuclear receptor coactivator 1	hepatocyte nuclear factor 4, gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm
	Molecular Function	Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Intracellular Receptor Signaling Pathway Endocrine Pancreas Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated
Pathways			Regulation of beta-cell development Generic Transcription Pathway Regulation of gene expression in beta cells Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS			Body mass index ( 20935630) Breast cancer ( 23535729) Obesity ( 23563607) Urate levels ( 23263486)
Protein-Protein Interactions		12 interactors: AR ESR2 ESRRG GRB2 HNF4A HNF4G MAPK8 NR5A2 RARB RARG RORA RORB	14 interactors: COPS5 EIF3I GAPDH HAX1 HLF NCOA1 NR0B2 NSD1 PNRC1 PNRC2 PRDX6 RANBP9 SRC TNNI2
Entrez ID		10957	3174
HPRD ID		08412	06909
Ensembl ID		ENSG00000146278	ENSG00000164749
Uniprot IDs		Q12796	F1D8Q4 Q14541
PDB IDs			1LV2
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Lipid Cellular Response To Hormone Stimulus Cellular Response To Organic Cyclic Compound Response To Steroid Hormone Response To Lipid Response To Hormone Cellular Response To Organic Substance Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Response To Organic Substance Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Signal Transduction Signaling Cell Communication Organ Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Response To Stimulus Retinoic Acid Receptor Signaling Pathway Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process System Development Endocrine Pancreas Development Response To Stimulus Nucleobase-containing Compound Metabolic Process Retinal Pigment Epithelium Development Multicellular Organismal Development Prostate Gland Development	Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Response To Progesterone Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Peptidyl-cysteine S-trans-nitrosylation Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Protein Kinase B Signaling RNA Metabolic Process Cellular Response To Progesterone Stimulus Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cellular Response To Drug Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Targeting To Mitochondrion Exosomal Secretion Response To Steroid Hormone Regulation Of Protein Kinase B Signaling Peptidyl-cysteine S-nitrosylation Positive Regulation Of Integrin Activation Positive Regulation Of Podosome Assembly Regulation Of Response To Drug Negative Regulation Of Mitochondrial Depolarization Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Negative Regulation Of Protein Homooligomerization Progesterone Receptor Signaling Pathway Positive Regulation Of Female Receptivity Regulation Of Podosome Assembly Cellular Response To Hormone Stimulus Male Mating Behavior Regulation Of Caveolin-mediated Endocytosis Mammary Gland Development
Tagcloud ?			5th adcy9 ancestry broader classes etiological exploiting extremes generalizable gnat2 h6pd height hip hs6st3 igfbp4 influencing loci mrps33p4 obesity overlap percentiles ppp2r2a rptor rsrc1 tails trait traits waist zzz3
Tagcloud (Difference) ?			5th adcy9 ancestry broader classes etiological exploiting extremes generalizable gnat2 h6pd height hip hs6st3 igfbp4 influencing loci mrps33p4 obesity overlap percentiles ppp2r2a rptor rsrc1 tails trait traits waist zzz3
Tagcloud (Intersection) ?