ENPP5 and PTK7

		ENPP5	PTK7
Description		ectonucleotide pyrophosphatase/phosphodiesterase family member 5	protein tyrosine kinase 7 (inactive)
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane	Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Membrane Axon Neuronal Cell Body Anchoring Junction
	Molecular Function	NAD+ Diphosphatase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding	Protein Kinase Activity Protein Binding ATP Binding Axon Guidance Receptor Activity Coreceptor Activity
	Biological Process	Cell Communication	Establishment Of Planar Polarity Kidney Development Neural Tube Closure Ventricular Septum Development Axis Elongation Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Axon Guidance Heart Development Positive Regulation Of Neuron Projection Development Wnt Signaling Pathway Cell Migration Actin Cytoskeleton Organization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Synapse Organization Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Coronary artery disease ( 29212778)
Interacting Genes		2 interacting genes: CFTR TIAM1	41 interacting genes: CDC14A CLNK CTDSP2 CYSRT1 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP5-9 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2
Entrez ID		59084	5754
HPRD ID		13272	03534
Ensembl ID		ENSG00000112796	ENSG00000112655
Uniprot IDs		B4DHN2 Q9UJA9	Q13308
PDB IDs		5VEM	6VG3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Cell-cell Junction Positive Regulation Of Enamel Mineralization Wnt Signaling Pathway Transepithelial Water Transport Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Cell Projection Organization Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Lung-associated Mesenchyme Development Axon Guidance Receptor Activity Regulation Of Neuron Projection Development Anchoring Junction Regulation Of Dopaminergic Neuron Differentiation Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Cellular Response To Lipid Convergent Extension Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Establishment Of Epithelial Cell Apical/basal Polarity Axis Elongation Chloride Transmembrane Transporter Activity Sperm Capacitation Water Transport Bicarbonate Transport Regulation Of Plasma Membrane Bounded Cell Projection Organization Establishment Of Planar Polarity Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Coronary Vasculature Development Regulation Of Cell Projection Organization Rac Protein Signal Transduction Cell-cell Contact Zone Cochlea Morphogenesis Multicellular Organismal-level Water Homeostasis Establishment Of Epithelial Cell Polarity	Phosphoprotein Phosphatase Activity Dephosphorylation Protein Serine/threonine Phosphatase Activity Protein Dephosphorylation Protein Tyrosine Phosphatase Activity Hydrolase Activity Phosphate-containing Compound Metabolic Process Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Calmodulin-dependent Protein Phosphatase Activity Cation Binding Peptidyl-tyrosine Dephosphorylation Non-membrane Spanning Protein Tyrosine Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Regulation Of ERK1 And ERK2 Cascade Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Protein Modification Process MAP Kinase Phosphatase Activity Phosphatidylinositol Dephosphorylation Regulation Of MAPK Cascade Cytoplasm Phospholipid Dephosphorylation Regulation Of Intracellular Signal Transduction Phosphatidylinositol-3-phosphate Phosphatase Activity Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of MAPK Cascade Negative Regulation Of Epithelial Cell Migration Cytosol Phosphatidylinositol Metabolic Process N-terminal Protein Myristoylation Regulation Of Epithelial Cell Migration Negative Regulation Of T Cell Proliferation Negative Regulation Of Signaling Phosphatidylinositol Phosphate Phosphatase Activity Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Phosphatidylinositol Dephosphorylation Regulation Of Mononuclear Cell Proliferation Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Regulation Of Lymphocyte Activation Protein Metabolic Process Negative Regulation Of Lymphocyte Proliferation Regulation Of Leukocyte Proliferation Negative Regulation Of Lymphocyte Activation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Neutrophil Activation Negative Regulation Of Developmental Growth Regulation Of Oligodendrocyte Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?