ENPP5

Description		ectonucleotide pyrophosphatase/phosphodiesterase family member 5
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane
	Molecular Function	NAD+ Diphosphatase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Cell Communication
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Novel Interacting Genes		1 novel interacting genes: PTK7
Interacting Genes		2 interacting genes: CFTR TIAM1
Entrez ID		59084
HPRD ID		13272
Ensembl ID		ENSG00000112796
Uniprot IDs		B4DHN2 Q9UJA9
PDB IDs		5VEM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Cell-cell Junction Positive Regulation Of Enamel Mineralization Wnt Signaling Pathway Transepithelial Water Transport Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Cell Projection Organization Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Lung-associated Mesenchyme Development Axon Guidance Receptor Activity Regulation Of Neuron Projection Development Anchoring Junction Regulation Of Dopaminergic Neuron Differentiation Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Cellular Response To Lipid Convergent Extension Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Establishment Of Epithelial Cell Apical/basal Polarity Axis Elongation Chloride Transmembrane Transporter Activity Sperm Capacitation Water Transport Bicarbonate Transport Regulation Of Plasma Membrane Bounded Cell Projection Organization Establishment Of Planar Polarity Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Coronary Vasculature Development Regulation Of Cell Projection Organization Rac Protein Signal Transduction Cell-cell Contact Zone Cochlea Morphogenesis Multicellular Organismal-level Water Homeostasis Establishment Of Epithelial Cell Polarity
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