SWSAP1 and EPM2AIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SWSAP1	EPM2AIP1
Description		SWIM-type zinc finger 7 associated protein 1	EPM2A interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Shu Complex	Nucleus Cytoplasm Endoplasmic Reticulum Cytoplasmic Side Of Endoplasmic Reticulum Membrane
	Molecular Function	DNA Binding Single-stranded DNA Binding Protein Binding ATP Hydrolysis Activity	Protein Binding Identical Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination DNA Damage Response Protein Stabilization	Glycogen Biosynthetic Process Response To Insulin Positive Regulation Of Glycogen Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Autism spectrum disorder or schizophrenia ( 28540026) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Subjective response to lithium treatment ( 26503763) Triglyceride levels ( 32203549)
Interacting Genes		8 interacting genes: A2M EPM2AIP1 RAD51 RAD51B RAD51C RAD51D SPG21 XRCC3	47 interacting genes: ACTN1 APPL2 ARHGEF5 C1orf50 CBFA2T3 CCNB1IP1 CNTROB CPSF7 DTX3 EMP2 EPM2A FHL3 GFAP HSF2BP KCTD1 KCTD9 KRT16 KRT75 LDB2 LIN52 LNX1 MAD2L1 MEOX2 MX1 NOC4L OTUD7B PICK1 PRTFDC1 PSMA7 RBMY1F RBMY1J REL SERPINF1 SWSAP1 TFIP11 TNFAIP1 TNKS TRA2B TRIM50 TRIM54 USP54 VPS52 WEE2-AS1 ZBTB14 ZIM2 ZNF620 ZSCAN18
Entrez ID		126074	9852
HPRD ID		08179	07445
Ensembl ID		ENSG00000173928	ENSG00000178567
Uniprot IDs		A0A6I8PRB2 Q6NVH7	Q7L775
PDB IDs
Enriched GO Terms of Interacting Partners?		ATP-dependent DNA Damage Sensor Activity Telomere Maintenance Via Recombination Four-way Junction DNA Binding Mitotic Recombination Rad51B-Rad51C-Rad51D-XRCC2 Complex Reciprocal Meiotic Recombination Replication Fork Double-strand Break Repair Via Homologous Recombination Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination Telomere Maintenance Rad51C-XRCC3 Complex Telomere Organization ATP-dependent Activity, Acting On DNA Interstrand Cross-link Repair DNA Repair DNA Strand Invasion DNA Recombinase Assembly Crossover Junction DNA Endonuclease Activity DNA Metabolic Process DNA Damage Response Chromosome Organization Single-stranded DNA Binding Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Chromosome, Telomeric Region Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G2/M Phase Transition Meiosis I ATP Binding Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Process Cellular Response To Stress Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Nucleotide Binding Meiosis I Cell Cycle Process Response To Glucoside Female Meiosis Sister Chromatid Cohesion Meiotic Nuclear Division Negative Regulation Of Complement Activation, Lectin Pathway Mitotic Recombination-dependent Replication Fork Processing Nuclear Division Macromolecule Metabolic Process DNA Strand Exchange Activity Presynaptic Intermediate Filament Cytoskeleton Nucleic Acid Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition	Identical Protein Binding Positive Regulation Of MRNA Splicing, Via Spliceosome
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