RSC1A1 and ODC1

Number of citations of the paper that reports this interaction (PubMedID 27555600)
0

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		RSC1A1	ODC1
Description		regulator of solute carriers 1	ornithine decarboxylase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Plasma Membrane Membrane Cell Junction	Cytoplasm Cytosol
	Molecular Function	Protein Binding Sodium Channel Inhibitor Activity	Catalytic Activity Ornithine Decarboxylase Activity Protein Binding Lyase Activity Carboxy-lyase Activity Protein Homodimerization Activity
	Biological Process	Negative Regulation Of D-glucose Transmembrane Transport Negative Regulation Of Nucleoside Transport Negative Regulation Of Golgi To Plasma Membrane Protein Transport Negative Regulation Of Transport Negative Regulation Of Protein Localization To Plasma Membrane	Kidney Development Polyamine Metabolic Process Polyamine Biosynthetic Process Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Response To Virus Putrescine Biosynthetic Process From Arginine, Via Ornithine Regulation Of Protein Catabolic Process
Pathways		SLC-mediated transport of organic cations Intestinal hexose absorption	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs			Pyridoxal phosphate Spermine Sildenafil Valproic acid Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		3 interacting genes: LSM8 ODC1 RAD23B	17 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510
Entrez ID		6248	4953
HPRD ID		15994	01324
Ensembl ID		ENSG00000215695	ENSG00000115758
Uniprot IDs		Q92681	B4DXF8 P11926
PDB IDs			1D7K 2ON3 2OO0 4ZGY 5BWA 7S3F 7S3G 7U6P 7U6U 9B8M 9B8N
Enriched GO Terms of Interacting Partners?		MAML1-RBP-Jkappa- ICN1 Complex Positive Regulation Of Ephrin Receptor Signaling Pathway Club Cell Differentiation Epidermal Cell Fate Specification Endocardium Morphogenesis RNA Polymerase II-specific DNA-binding Transcription Factor Binding Embryonic Organ Development Pulmonary Valve Development Blood Vessel Endothelial Cell Fate Specification Blood Vessel Lumenization Arterial Endothelial Cell Fate Commitment Endothelial Cell Fate Specification Auditory Receptor Cell Fate Commitment Regulation Of Cell Adhesion Involved In Heart Morphogenesis Ornithine Decarboxylase Activity Putrescine Biosynthetic Process From Arginine, Via Ornithine DNA Damage Sensor Activity XPC Complex Endocardium Development Putrescine Biosynthetic Process Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Aortic Valve Development Hair Follicle Maturation Semi-lunar Valve Development Positive Regulation Of Transcription Of Notch Receptor Target Lsm2-8 Complex Sebaceous Gland Development Dorsal Aorta Morphogenesis Putrescine Metabolic Process Animal Organ Development U6 SnRNP Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Ventricular Trabecula Myocardium Morphogenesis Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic Cardiac Muscle Cell Myoblast Differentiation Endothelial Tube Morphogenesis Heart Field Specification Atrioventricular Canal Development Epithelial Cell Fate Commitment Secondary Heart Field Specification Cardioblast Differentiation Cardiac Left Ventricle Morphogenesis Polyamine Biosynthetic Process Regulation Of Protein Catabolic Process Cellular Response To Interleukin-7 U6 SnRNA Binding Response To Interleukin-7 Specification Of Animal Organ Identity Regulation Of Cell Proliferation Involved In Heart Morphogenesis	Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Viral Translational Frameshifting Polyamine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Transmembrane Transport Golgi Organization Viral Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process
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