PAQR3

Description		progestin and adipoQ receptor family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Negative Regulation Of Protein Phosphorylation NLS-bearing Protein Import Into Nucleus Negative Regulation Of Neuron Projection Development Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Peptidyl-serine Phosphorylation Protein Localization To Golgi Apparatus Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of MAP Kinase Activity Positive Regulation Of Cholesterol Biosynthetic Process Protein Maturation Positive Regulation Of SREBP Signaling Pathway
Pathways		Negative regulation of MAPK pathway
Drugs
Diseases
GWAS		Chronotype ( 30696823) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Parkinson's disease ( 26227905)
Novel Interacting Genes		1 novel interacting genes: FRAS1
Interacting Genes		3 interacting genes: BTRC PPARA RAD23B
Entrez ID		152559
HPRD ID		17819
Ensembl ID		ENSG00000163291
Uniprot IDs		Q6TCH7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Appetite Response To Nutrient Levels Negative Regulation Of Glycolytic Process Regulation Of Circadian Rhythm Cellular Response To Fructose Stimulus Animal Organ Development Negative Regulation Of Cholesterol Storage Regulation Of Response To Food MDM2/MDM4 Family Protein Binding Enamel Mineralization Response To Fructose Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Hepatocyte Apoptotic Process Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of Catabolic Process Regulation Of Transformation Of Host Cell By Virus Cellular Response To Nutrient Levels Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of ATP Biosynthetic Process Tooth Mineralization Rhythmic Process NFAT Protein Binding Positive Regulation Of Transformation Of Host Cell By Virus Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of ATP Biosynthetic Process Behavioral Response To Nicotine Positive Regulation Of Fatty Acid Beta-oxidation Mitogen-activated Protein Kinase Kinase Kinase Binding Positive Regulation Of Fatty Acid Oxidation Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process DNA Damage Sensor Activity Cellular Response To Interleukin-7 Proteasomal Protein Catabolic Process Proteasome Binding XPC Complex Regulation Of Protein Catabolic Process Response To Interleukin-7 Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Circadian Rhythm Ubiquitin Ligase Activator Activity Mammary Gland Epithelial Cell Proliferation Morphogenesis Of An Epithelium Protein Phosphorylated Amino Acid Binding Tissue Morphogenesis Positive Regulation Of T Cell Receptor Signaling Pathway
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