RAC3 and NRBP1

Number of citations of the paper that reports this interaction (PubMedID 11956649)
0

Data Source:
HPRD (in vitro)

		RAC3	NRBP1
Description		Rac family small GTPase 3	nuclear receptor binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Endomembrane System Membrane Lamellipodium Growth Cone Cytoplasmic Vesicle Filamentous Actin Cell Projection Neuron Projection NADPH Oxidase Complex Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery Postsynapse Glutamatergic Synapse	Nucleoplasm Cytoplasm Cell Cortex Endomembrane System Membrane Lamellipodium Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Protein Kinase Binding Calcium-dependent Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase-mediated Signal Transduction Motor Neuron Axon Guidance Regulation Of Cell Shape Regulation Of Cell-substrate Adhesion Regulation Of Neuron Maturation Wnt Signaling Pathway Rac Protein Signal Transduction Cerebral Cortex GABAergic Interneuron Development Regulation Of Cell Morphogenesis Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Respiratory Burst Homeostasis Of Number Of Cells Within A Tissue Neuromuscular Process Controlling Balance Neuromuscular Process Synaptic Transmission, GABAergic Cell Chemotaxis Postsynaptic Actin Cytoskeleton Organization Regulation Of Postsynapse Assembly Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Neutrophil Migration	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport DNA Damage Response
Pathways		PCP/CE pathway RAC3 GTPase cycle	Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Bone mineral density (total hip) ( 29883787) Creatinine levels ( 31015462) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Takayasu arteritis ( 25604533)
Interacting Genes		9 interacting genes: ANKRD11 AR ARFIP2 ARHGDIB CIB1 ESR1 HDAC7 HNF1A NRBP1	17 interacting genes: BCL2L13 BTG3 CDKN1A CIMIP5 CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 SNX31 SORBS3 TIAM1 TK1 TSC22D4
Entrez ID		5881	29959
HPRD ID		03629	05819
Ensembl ID		ENSG00000169750	ENSG00000115216
Uniprot IDs		P60763	F8W6G1 Q9UHY1
PDB IDs		2C2H 2G0N 2IC5 2OV2 2QME 6TM1
Enriched GO Terms of Interacting Partners?		Regulation Of Reproductive Process Estrogen Response Element Binding Prostate Gland Growth Cellular Response To Estrogen Stimulus Mammary Gland Alveolus Development Prostate Gland Epithelium Morphogenesis Estrogen Receptor Signaling Pathway Nuclear Steroid Receptor Activity Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Steroid Binding 14-3-3 Protein Binding Prostate Induction Organ Growth Transcription Coactivator Binding Nuclear Receptor Activity Response To Estrogen Male Somatic Sex Determination Regulation Of Morphogenesis Of A Branching Structure Small GTPase Binding Positive Regulation Of Male Germ Cell Proliferation Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Morphogenesis Of An Epithelium Regulation Of MiRNA Transcription Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of Reproductive Process Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis ATPase Binding Regulation Of MiRNA Metabolic Process Regulation Of Pronephros Size Beta-catenin Binding Regulation Of Protein Localization To Plasma Membrane Chromatin Binding Male Genitalia Morphogenesis Cytoplasm POU Domain Binding Male Gonad Development Nuclear Receptor-mediated Signaling Pathway Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Integrin Biosynthetic Process Rho GDP-dissociation Inhibitor Activity Cellular Response To Redox State Nuclear Estrogen Receptor Activity TFIIB-class Transcription Factor Binding Prostate Epithelial Cord Elongation Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of DNA-binding Transcription Factor Activity	Intracellular Signaling Cassette Wnt Signaling Pathway Regulation Of Dopaminergic Neuron Differentiation
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