RAC3 and ARHGDIB

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RAC3	ARHGDIB
Gene Name		ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	Rho GDP dissociation inhibitor (GDI) beta
Image
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Endomembrane System Lamellipodium Growth Cone Filamentous Actin Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery	Cytoplasm Cytosol Cytoskeleton Cytoplasmic Membrane-bounded Vesicle Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Calcium-dependent Protein Binding	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity
	Biological Process	Small GTPase Mediated Signal Transduction Metabolic Process Cell Projection Assembly Actin Cytoskeleton Organization Neuron Projection Development Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	Movement Of Cell Or Subcellular Component Immune Response Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Multicellular Organismal Development Actin Cytoskeleton Organization Positive Regulation Of GTPase Activity Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Signaling by Rho GTPases Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling	Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ANKRD11 AR ARHGDIA ARHGDIB CIB1 ESR1 HNF1A NRBP1 RARA	11 interactors: APP CASP3 CDC42 EZR RAC1 RAC2 RAC3 RHOA RHOH UFM1 VAV1
Entrez ID		5881	397
HPRD ID		03629	04162
Ensembl ID		ENSG00000169750	ENSG00000111348
Uniprot IDs		P60763	P52566
PDB IDs		2C2H 2G0N 2IC5 2OV2 2QME	1DS6
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Prostate Gland Development Intracellular Steroid Hormone Receptor Signaling Pathway Developmental Process Involved In Reproduction Steroid Hormone Mediated Signaling Pathway Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Hormone-mediated Signaling Pathway Regulation Of Signaling Multicellular Organismal Development Intracellular Estrogen Receptor Signaling Pathway Growth Gland Development Reproductive Structure Development Reproductive System Development Cellular Response To Steroid Hormone Stimulus Single Organism Reproductive Process Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Regulation Of Cell Adhesion Reproductive Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Regulation Of Apoptotic Process Response To Organic Substance Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Cell Death System Development Regulation Of Protein Localization Sex Differentiation Positive Regulation Of Cell Proliferation Face Development Regulation Of Protein Localization To Plasma Membrane Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Intracellular Signal Transduction Rho Protein Signal Transduction Negative Regulation Of Apoptotic Process Organ Development Negative Regulation Of Programmed Cell Death Cellular Response To Organic Substance Negative Regulation Of Cell Death Urogenital System Development Organ Morphogenesis Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Male Germ Cell Proliferation	Chemotaxis Small GTPase Mediated Signal Transduction Neuron Differentiation Response To Wounding Cell Morphogenesis Involved In Differentiation Axon Guidance Regulation Of Small GTPase Mediated Signal Transduction Blood Coagulation Hemostasis Platelet Activation Neuron Projection Development Generation Of Neurons Neuron Development Axonogenesis Axon Development Neurogenesis Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Morphogenesis Wound Healing Actin Cytoskeleton Organization Cell Projection Assembly Regulation Of Cell Adhesion Neuron Projection Morphogenesis Cell Development Actin Filament-based Process Cell Projection Organization Regulation Of Signal Transduction Intracellular Signal Transduction Cell Adhesion Cell Activation Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Locomotion Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Signaling Positive Regulation Of Cell Morphogenesis Involved In Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Nervous System Development Movement Of Cell Or Subcellular Component Cell Differentiation Regulation Of Cell Morphogenesis Regulation Of Cell-substrate Adhesion Anatomical Structure Morphogenesis Neurotrophin TRK Receptor Signaling Pathway Single Organismal Cell-cell Adhesion Neurotrophin Signaling Pathway Regulation Of Intracellular Signal Transduction Epithelium Development
Tagcloud ?		accessible acetyltransferases aspects cloned coactivator concert condensed cor corepressor corepressors deacetylases entry era establish extensively generate hormone initiate modulate replaced repressed repression smrt src1 steroid theme tif2 transcriptionally unliganded	address affecting autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 nme3 oncogene oncogenic proto rescued solid timp1 timp2 turnover
Tagcloud (Difference) ?		accessible acetyltransferases aspects cloned coactivator concert condensed cor corepressor corepressors deacetylases entry era establish extensively generate hormone initiate modulate replaced repressed repression smrt src1 steroid theme tif2 transcriptionally unliganded	address affecting autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 nme3 oncogene oncogenic proto rescued solid timp1 timp2 turnover
Tagcloud (Intersection) ?