PMM1

Description		phosphomannomutase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Neuronal Cell Body
	Molecular Function	Phosphomannomutase Activity Protein Binding Isomerase Activity Metal Ion Binding
	Biological Process	Mannose Metabolic Process Protein N-linked Glycosylation GDP-mannose Biosynthetic Process Nucleoside Phosphate Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor
Pathways		Synthesis of GDP-mannose
Drugs
Diseases
GWAS		Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: RBX1
Interacting Genes		5 interacting genes: CACNA1A MFHAS1 RAB6A RAB6B RCHY1
Entrez ID		5372
HPRD ID		03473
Ensembl ID		ENSG00000100417
Uniprot IDs		Q92871
PDB IDs		2FUC 2FUE 6CFR 6CFS 6CFT 6CFU 6CFV
Enriched GO Terms of Interacting Partners?		Protein Localization To Golgi Membrane Myosin V Binding Protein Localization To Golgi Apparatus Intra-Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum GTP Binding Peptidyl-cysteine Methylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cytosolic Transport Retrograde Transport, Endosome To Golgi Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Post-translational Protein Modification Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Autoubiquitination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process VCB Complex Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Protein Catabolic Process Minus-end-directed Organelle Transport Along Microtubule NEDD8 Ligase Activity Cul7-RING Ubiquitin Ligase Complex Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process Base-excision Repair, AP Site Formation Via Deaminated Base Removal NEDD8 Transferase Activity Error-free Translesion Synthesis Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Autoubiquitination Regulation Of Protein Ubiquitination Cul4B-RING E3 Ubiquitin Ligase Complex Positive Regulation Of Protein Catabolic Process Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Post-translational Protein Modification Negative Regulation Of Response To Oxidative Stress Ubiquitin-protein Transferase Activity Endosomal Transport Endomembrane System Golgi Vesicle Transport Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway Negative Regulation Of Mitophagy Transcription-coupled Nucleotide-excision Repair High Voltage-gated Calcium Channel Activity Protein Localization To Membrane Ubiquitin Protein Ligase Binding GTPase Activity Ciliary Basal Body Cul4A-RING E3 Ubiquitin Ligase Complex Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
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