WIZ and SLC44A2

		WIZ	SLC44A2
Description		WIZ zinc finger	solute carrier family 44 member 2 (CTL2 blood group)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody Extracellular Exosome	Mitochondrion Mitochondrial Outer Membrane Lysosomal Membrane Plasma Membrane Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding Protein Binding Zinc Ion Binding Protein-containing Complex Binding Metal Ion Binding Histone Methyltransferase Binding	Choline Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity Ethanolamine Transmembrane Transporter Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization	Phosphatidylcholine Biosynthetic Process Choline Transport Ethanolamine Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction Transmembrane Transport
Pathways			Synthesis of PC Neutrophil degranulation SLC-mediated bile acid transport
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte percentage of white cells ( 32888494)	Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Bipolar disorder ( 31043756) Height ( 31562340) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 24076602) Platelet count ( 29403010 32888494) Platelet distribution width ( 27863252 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Thrombosis ( 26908601) Venous thromboembolism ( 31676865 25772935)
Interacting Genes		17 interacting genes: C8orf33 CDKN1A CRBN DOK5 EHMT1 EHMT2 OSGEP PIN1 PKNOX1 RCC1 RPP14 RPS10 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1	2 interacting genes: BDKRB1 HTR2B
Entrez ID		58525	57153
HPRD ID		11686	16198
Ensembl ID		ENSG00000011451	ENSG00000129353
Uniprot IDs		A0A2R8YFV2 A0A669KAV7 A0A669KBG4 A0A669KBH9 M0QXA7 O95785	A0A088QCU6 Q8IWA5
PDB IDs		8TZX 9DJT 9DJX
Enriched GO Terms of Interacting Partners?		Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Methyltransferase Activity Histone H3K9me2 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity Peptidyl-lysine Dimethylation Histone H3K27 Methyltransferase Activity Negative Regulation Of Gene Expression, Epigenetic Methyltransferase Activity Methylation Nucleus Facultative Heterochromatin Formation Epigenetic Programming In The Zygotic Pronuclei C2H2 Zinc Finger Domain Binding Peptidyl-lysine Methylation Epigenetic Regulation Of Gene Expression Protein-lysine N-methyltransferase Activity Cellular Response To Hypoxia Heterochromatin Formation Cellular Response To Decreased Oxygen Levels Nuclear Body Nucleoplasm Chromosome Cellular Response To Oxygen Levels Epigenetic Programming Of Gene Expression Protein Methylation DNA Methylation-dependent Constitutive Heterochromatin Formation Macromolecule Metabolic Process Cellular Response To Starvation Cis-trans Isomerase Activity Histone H3K56 Methyltransferase Activity Transcription Corepressor Binding Condensed Nuclear Chromosome Response To Starvation Constitutive Heterochromatin Formation PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Thymidine Kinase Activity TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity RNA Metabolic Process Cellular Response To Nutrient Levels Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Nucleic Acid Metabolic Process ENoSc Complex DNA Synthesis Involved In Mitotic DNA Replication Phenotypic Switching P53 Binding Ethanolamine Transport Ethanolamine Transmembrane Transporter Activity	Phylloquinone Catabolic Process Menaquinone Metabolic Process Menaquinone Catabolic Process Vitamin K Catabolic Process Vitamin K Metabolic Process Ketone Catabolic Process Vitamin Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Regulation Of Biological Quality Arachidonate Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Monooxygenase Activity Ketone Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Icosanoid Metabolic Process Bradykinin Receptor Activity Oxylipin Biosynthetic Process Iron Ion Binding Heme Binding Regulation Of Sequestering Of Calcium Ion Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process Olefinic Compound Metabolic Process Pressure Natriuresis G Protein-coupled Serotonin Receptor Complex Intestine Smooth Muscle Contraction Arachidonate Omega-hydroxylase Activity Cytochrome Metabolic Process Leukotriene B4 Catabolic Process Leukotriene B4 Metabolic Process Leukotriene-B4 20-monooxygenase Activity Alkane 1-monooxygenase Activity Vitamin E Metabolic Process Long-chain Fatty Acid Omega-hydroxylase Activity Positive Regulation Of Nuclear Cell Cycle DNA Replication Phospholipase C-activating Serotonin Receptor Signaling Pathway Long-chain Fatty Acid Catabolic Process Serotonin Binding Serotonin Receptor Signaling Pathway Omega-hydroxylase P450 Pathway Arachidonate Epoxygenase Activity Positive Regulation Of Phospholipid Biosynthetic Process Serotonin Receptor Activity Neural Crest Cell Differentiation GTPase Inhibitor Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen G Protein-coupled Serotonin Receptor Activity Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Body Fluid Levels
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