BIN3 and RPRD1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BIN3	RPRD1B
Description		bridging integrator 3	regulation of nuclear pre-mRNA domain containing 1B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Actin Cytoskeleton	Nucleus Nucleoplasm Transcription Preinitiation Complex
	Molecular Function	Protein Binding Cytoskeletal Anchor Activity Lipid Binding	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding RNA Polymerase II C-terminal Domain Binding
	Biological Process	Endocytosis Actin Filament Organization Intracellular Protein Localization Unidimensional Cell Growth Regulation Of Lamellipodium Assembly Myoblast Migration Involved In Skeletal Muscle Regeneration Skeletal Muscle Tissue Regeneration Developmental Growth Skeletal Muscle Fiber Development Cell Division Actin Cortical Patch Localization Cytoskeleton-dependent Cytokinesis Plasma Membrane Tubulation	RNA Polymerase II Promoter Clearance Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing Positive Regulation Of Transcription By RNA Polymerase II
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Cataracts ( 34127677) Estimated glomerular filtration rate ( 31152163) Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Heel bone mineral density ( 30598549) Parkinson's disease ( 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		9 interacting genes: ABI2 C14orf119 GINS4 NXF1 POLR1C RPRD1B TRIM69 TXLNA UBL5	22 interacting genes: BIN3 CDCA8 DDIT4L EIF4ENIF1 HMG20A HMGB3 HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 SPG21 STAT3 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C WEE2-AS1
Entrez ID		55909	58490
HPRD ID		05904	08513
Ensembl ID		ENSG00000147439	ENSG00000101413
Uniprot IDs		E5RHU4 H7BYV6 Q9NQY0	Q9NQG5
PDB IDs			4FLA 4FU3 4HFG 4NAD 4Q94 4Q96 9B9L
Enriched GO Terms of Interacting Partners?			Import Into Nucleus Protein Import Into Nucleus Nuclear Transport Nucleocytoplasmic Transport Cellular Localization Intracellular Protein Transport Establishment Of Protein Localization To Organelle Intracellular Transport Protein Localization To Nucleus Protein Localization To Organelle Membrane Organization Negative Regulation Of Cell Differentiation Nuclear Import Signal Receptor Activity Establishment Of Localization In Cell Nuclear Export Negative Regulation Of Developmental Process Astrocyte Differentiation Intracellular Protein Localization Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair SUMO Conjugating Enzyme Activity Actin Cortical Patch Localization Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
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