ZNF410 and IQUB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF410	IQUB
Description		zinc finger protein 410	IQ motif and ubiquitin domain containing
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GO Annotations	Cellular Component	Nucleus Chromosome	Radial Spoke Acrosomal Vesicle Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection 9+2 Motile Cilium
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Oxygen Transport Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Smoothened Signaling Pathway Mating Cell Projection Organization Flagellated Sperm Motility Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Serum uric acid levels ( 29559957)
Interacting Genes		54 interacting genes: ABHD8 APP BANP BLZF1 CCNG2 CDKN2A CEP70 CSNK2B DPEP2NB DVL2 FAM9B FHL2 FSD2 GOLGA2 GOLGA6L9 HOXB2 IQUB IRAK1BP1 KRT40 LIMS1 LMO2 LMO4 LNX2 LRIF1 MEOX1 MEOX2 MID2 MTUS2 NDUFAB1 NOSIP OSM PAX6 PDE4DIP PICK1 PNMA1 POGZ POLR2G POLR2M POU6F2 PPM1K PPP1R16B PRKAR1B RAB3IP RASSF3 RCN1 RPRD1A SERTAD1 TRAF2 TRIM35 TSGA10 UHRF2 VBP1 ZNF24 ZNF397	58 interacting genes: ALX4 ANAPC11 ANKRD23 BLZF1 CALCOCO2 CEP70 CEP76 CFTR CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 GPRASP3 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1
Entrez ID		57862	154865
HPRD ID		18339	08194
Ensembl ID		ENSG00000119725	ENSG00000164675
Uniprot IDs		Q53FM1 Q86VK4	Q8NA54
PDB IDs		6WMI	2DAF 8J07
Enriched GO Terms of Interacting Partners?		Segment Specification Nucleus Cytoplasm Identical Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Somite Specification	Intermediate Filament Ubiquitin Protein Ligase Activity Keratin Filament Identical Protein Binding Zinc Ion Binding Protein Binding Protein K63-linked Ubiquitination Microtubule Ubiquitin-protein Transferase Activity
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