IQUB and IHO1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		IQUB	IHO1
Description		IQ motif and ubiquitin domain containing	interactor of HORMAD1 1
Image			No pdb structure
GO Annotations	Cellular Component	Radial Spoke Acrosomal Vesicle Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection 9+2 Motile Cilium	Condensed Nuclear Chromosome Chromosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Smoothened Signaling Pathway Mating Cell Projection Organization Flagellated Sperm Motility Cilium Assembly	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Cell Differentiation Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Cell Cycle Regulation Of Homologous Chromosome Segregation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		58 interacting genes: ALX4 ANAPC11 ANKRD23 BLZF1 CALCOCO2 CEP70 CEP76 CFTR CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 GPRASP3 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1	78 interacting genes: ABI2 ABI3 ADAMTS12 AIRIM AQP1 ARHGEF9 ATP6V0D1 BCL6 BOLA2 BOLA2B CARD9 CCDC120 CCDC57 CDC23 CFAP206 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 EXOC8 FAM124A FAM124B FANCG FANCL FASLG FHL3 FKBP6 GEM GLRX3 GLYCTK GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KIF9 KIFC3 KLC3 KLHL11 LMO2 LNX1 LONRF1 MAGEB4 MAGOHB MAPK9 MID2 MRFAP1L1 MVP MYO15B NEK6 NFKBID NGB PICK1 POLR1C PRKAB2 PRR34 RABGEF1 RAD51D RHOBTB3 RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM14 TRIM42 TTC19 USP2 USP20 ZGPAT ZKSCAN3 ZNF417 ZNF688
Entrez ID		154865	339834
HPRD ID		08194	14172
Ensembl ID		ENSG00000164675	ENSG00000173421
Uniprot IDs		Q8NA54	B4DZP6 Q8IYA8
PDB IDs		2DAF 8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Ubiquitin Protein Ligase Activity Keratin Filament Identical Protein Binding Zinc Ion Binding Protein Binding Protein K63-linked Ubiquitination Microtubule Ubiquitin-protein Transferase Activity	Protein Binding Cytoplasm Identical Protein Binding [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Complex Negative Regulation Of Mast Cell Cytokine Production Cytoskeleton Microtubule-based Process Regulation Of Cellular Senescence Microtubule Centrosome Iron-sulfur Cluster Assembly Intracellular Iron Ion Homeostasis
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