IQUB and ANKRD23

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IQUB	ANKRD23
Description		IQ motif and ubiquitin domain containing	ankyrin repeat domain 23
Image			No pdb structure
GO Annotations	Cellular Component	Radial Spoke Acrosomal Vesicle Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection 9+2 Motile Cilium	Nucleus Nucleoplasm Cytoplasm Cytosol Intercalated Disc Actin Cytoskeleton Myofibril I Band
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding Protein Binding Titin Binding
	Biological Process	Smoothened Signaling Pathway Mating Cell Projection Organization Flagellated Sperm Motility Cilium Assembly	Fatty Acid Metabolic Process Response To Mechanical Stimulus Response To Muscle Stretch Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Sarcomere Organization
Pathways
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		58 interacting genes: ALX4 ANAPC11 ANKRD23 BLZF1 CALCOCO2 CEP70 CEP76 CFTR CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 GPRASP3 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1	20 interacting genes: CCDC102B CCDC57 CDCA7L CLIC3 ENKD1 FAM90A1 GRB2 HOOK1 HRAS IQUB KDM1A KIFC3 MIPOL1 MYPN NAP1L1 PIBF1 POLR3C SMARCD1 TRIM41 TTN
Entrez ID		154865	200539
HPRD ID		08194	12462
Ensembl ID		ENSG00000164675	ENSG00000163126
Uniprot IDs		Q8NA54	Q86SG2
PDB IDs		2DAF 8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Ubiquitin Protein Ligase Activity Keratin Filament Identical Protein Binding Zinc Ion Binding Protein Binding Protein K63-linked Ubiquitination Microtubule Ubiquitin-protein Transferase Activity	Cytoskeleton Organization Centrosome Cellular Response To Ionizing Radiation Schwann Cell Development Microtubule-based Process Muscle Alpha-actinin Binding Cilium Assembly Positive Regulation Of Multicellular Organismal Process Cilium Organization I Band Cellular Response To Gamma Radiation Response To Ionizing Radiation Plasma Membrane Bounded Cell Projection Assembly
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