ZNF410 and CCNG2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF410	CCNG2
Description		zinc finger protein 410	cyclin G2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Oxygen Transport Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	G1/S Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cell Cycle
Pathways			FOXO-mediated transcription of cell cycle genes
Drugs
Diseases
GWAS		Serum uric acid levels ( 29559957)	Hormone measurements ( 30576415)
Interacting Genes		54 interacting genes: ABHD8 APP BANP BLZF1 CCNG2 CDKN2A CEP70 CSNK2B DPEP2NB DVL2 FAM9B FHL2 FSD2 GOLGA2 GOLGA6L9 HOXB2 IQUB IRAK1BP1 KRT40 LIMS1 LMO2 LMO4 LNX2 LRIF1 MEOX1 MEOX2 MID2 MTUS2 NDUFAB1 NOSIP OSM PAX6 PDE4DIP PICK1 PNMA1 POGZ POLR2G POLR2M POU6F2 PPM1K PPP1R16B PRKAR1B RAB3IP RASSF3 RCN1 RPRD1A SERTAD1 TRAF2 TRIM35 TSGA10 UHRF2 VBP1 ZNF24 ZNF397	7 interacting genes: EFHC2 NRIP2 PPP2CA PTPA TASOR2 TCF7L2 ZNF410
Entrez ID		57862	901
HPRD ID		18339	04438
Ensembl ID		ENSG00000119725	ENSG00000138764
Uniprot IDs		Q53FM1 Q86VK4	Q16589
PDB IDs		6WMI
Enriched GO Terms of Interacting Partners?		Segment Specification Nucleus Cytoplasm Identical Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Somite Specification	Protein Phosphatase Type 2A Complex Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Small Molecule Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Negative Regulation Of Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Phosphoprotein Phosphatase Activity Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Negative Regulation Of Wnt Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Protein Tyrosine Phosphatase Activator Activity Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Beta-catenin-TCF7L2 Complex Catenin-TCF7L2 Complex Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Proteoglycan Biosynthetic Process Myoblast Fate Commitment Phosphatase Activator Activity Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Maintenance Of DNA Repeat Elements Armadillo Repeat Domain Binding Protein Serine/threonine Phosphatase Complex Peptidyl-threonine Dephosphorylation
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