IQUB and ZNF143

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IQUB	ZNF143
Description		IQ motif and ubiquitin domain containing	zinc finger protein 143
Image			No pdb structure
GO Annotations	Cellular Component	Radial Spoke Acrosomal Vesicle Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection 9+2 Motile Cilium	Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Smoothened Signaling Pathway Mating Cell Projection Organization Flagellated Sperm Motility Cilium Assembly	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Positive Regulation Of SnRNA Transcription By RNA Polymerase II
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS			Cutaneous squamous cell carcinoma ( 32041948) Height ( 31562340) Hip circumference ( 28552196)
Interacting Genes		58 interacting genes: ALX4 ANAPC11 ANKRD23 BLZF1 CALCOCO2 CEP70 CEP76 CFTR CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 GPRASP3 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1	21 interacting genes: EAF1 ENKD1 EXOSC1 FAM90A1 FHL2 IL16 IQUB LIN54 LMO1 LMO3 NUDT22 POGZ SNRPB SPANXN3 SUOX TAB2 TCAF1 TSC22D2 YJU2 ZNF438 ZNF512B
Entrez ID		154865	7702
HPRD ID		08194	04578
Ensembl ID		ENSG00000164675	ENSG00000166478
Uniprot IDs		Q8NA54	P52747
PDB IDs		2DAF 8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Ubiquitin Protein Ligase Activity Keratin Filament Identical Protein Binding Zinc Ion Binding Protein Binding Protein K63-linked Ubiquitination Microtubule Ubiquitin-protein Transferase Activity
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