CCAR2 and BAG2

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		CCAR2	BAG2
Gene Name		cell cycle and apoptosis regulator 2	BCL2-associated athanogene 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Mitochondrial Matrix DBIRD Complex
	Molecular Function	RNA Polymerase II Core Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding Poly(A) RNA Binding	Protein Binding Identical Protein Binding Chaperone Binding
	Biological Process	MRNA Processing Cellular Response To DNA Damage Stimulus Cell Cycle RNA Splicing Response To UV Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription, Elongation Cellular Response To Heat Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Mitochondrial Fragmentation Involved In Apoptotic Process Rhythmic Process Regulation Of Cellular Response To Heat Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of DNA Damage Checkpoint	Protein Folding Protein Metabolic Process
Pathways		Cellular response to heat stress Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BAG2 CEP170P1 HSPA8 HTRA2 IKBKB PRMT5 ZNF335	12 interactors: CCAR2 DNAJC6 HSPA1A HSPA4 HSPA8 MAPKAPK2 NOTCH3 PINK1 PPIH SLU7 WDR77 WDR83
Entrez ID		57805	9532
HPRD ID		09159	04859
Ensembl ID		ENSG00000158941
Uniprot IDs		Q8N163	B4DXE2 O95816
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Protein Metabolic Process Cellular Response To Heat Protein Metabolic Process Pentacyclic Triterpenoid Metabolic Process Negative Regulation Of Fibril Organization Response To Heat Histone Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Regulation Of Cellular Component Organization Regulation Of Fibril Organization Protein Methylation Response To Temperature Stimulus Regulation Of Organelle Organization Regulation Of Cell Cycle Peptidyl-amino Acid Modification Clathrin Coat Disassembly Neuron Development MRNA Splicing, Via Spliceosome Serine Phosphorylation Of STAT Protein RNA Splicing, Via Transesterification Reactions Neuron Differentiation Protein Folding Response To Herbicide Protein Autoprocessing Regulation Of Mitochondrion Degradation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Histone H4-R3 Methylation RNA Splicing Histone H3-K4 Trimethylation Endothelial Cell Activation I-kappaB Phosphorylation Cellular Response To Interferon-beta Histone Modification Peptidyl-arginine N-methylation Methylation MRNA Processing Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Chaperone Mediated Protein Folding Requiring Cofactor Response To Interferon-beta Generation Of Neurons Forebrain Development Histone Arginine Methylation Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Refolding Peptidyl-arginine Methylation Neurogenesis Regulation Of Histone H3-K4 Methylation Cellular Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway	Cellular Response To Heat Regulation Of Cellular Response To Heat Response To Heat MRNA Metabolic Process RNA Splicing Response To Temperature Stimulus MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Clathrin Coat Disassembly Gene Expression Response To Abiotic Stimulus RNA Metabolic Process Response To Unfolded Protein Regulation Of Protein Stability Cellular Response To Stress Protein Refolding Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Apoptotic Signaling Pathway Protein Folding Nucleobase-containing Compound Metabolic Process Response To Stress Positive Regulation Of DNA Damage Checkpoint Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Fibril Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Post-Golgi Vesicle-mediated Transport Mitochondrion Organization Protein Stabilization Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cellular Response To Hypoxia Cellular Heat Acclimation Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Fibril Organization Nitrogen Compound Metabolic Process Peptidyl-serine Phosphorylation Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Protein Import Into Mitochondrial Outer Membrane Positive Regulation Of Cellular Respiration Cellular Protein Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death MRNA 3'-splice Site Recognition Regulation Of Cellular Response To Hypoxia
Tagcloud ?		11s acetylation atm atr axis chk2 clarify contributes damage dbc1 ddr deleted depends inactivation indeed kiaa1967 link modification modifications preventing proteasome reduces reggamma ser247 sirt1 spreading thr454 transducer upon	abolished ameliorates athanogene balance collapse cytochrome dimer disassociation dj elucidated homodimer link modulating monomer monomerization mpp neurodegeneration neuroprotective overexpressed overexpressing parkinson partners pd phenylpyridinium prevents property pulldown strengthening
Tagcloud (Difference) ?		11s acetylation atm atr axis chk2 clarify contributes damage dbc1 ddr deleted depends inactivation indeed kiaa1967 modification modifications preventing proteasome reduces reggamma ser247 sirt1 spreading thr454 transducer upon	abolished ameliorates athanogene balance collapse cytochrome dimer disassociation dj elucidated homodimer modulating monomer monomerization mpp neurodegeneration neuroprotective overexpressed overexpressing parkinson partners pd phenylpyridinium prevents property pulldown strengthening
Tagcloud (Intersection) ?		link