CCAR2 and ZNF335

Number of citations of the paper that reports this interaction (PMID 19131338)
21

Data Source:
BioGRID (two hybrid)

		CCAR2	ZNF335
Gene Name		cell cycle and apoptosis regulator 2	zinc finger protein 335
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Mitochondrial Matrix DBIRD Complex	Nucleus Histone Methyltransferase Complex
	Molecular Function	RNA Polymerase II Core Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	MRNA Processing Cellular Response To DNA Damage Stimulus Cell Cycle RNA Splicing Response To UV Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription, Elongation Cellular Response To Heat Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Mitochondrial Fragmentation Involved In Apoptotic Process Rhythmic Process Regulation Of Cellular Response To Heat Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of DNA Damage Checkpoint	In Utero Embryonic Development Positive Regulation Of Neuroblast Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Brain Development Cerebral Cortex Neuron Differentiation Regulation Of Gene Expression, Epigenetic Neuron Projection Morphogenesis Brain Morphogenesis Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Neurogenesis Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation
Pathways		Cellular response to heat stress Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BAG2 CEP170P1 HSPA8 HTRA2 IKBKB PRMT5 ZNF335	4 interactors: CCAR2 CDK4 CDK6 NCOA6
Entrez ID		57805	63925
HPRD ID		09159	11709
Ensembl ID		ENSG00000158941	ENSG00000198026
Uniprot IDs		Q8N163	Q8IW09 Q9H4Z2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Protein Metabolic Process Cellular Response To Heat Protein Metabolic Process Pentacyclic Triterpenoid Metabolic Process Negative Regulation Of Fibril Organization Response To Heat Histone Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Regulation Of Cellular Component Organization Regulation Of Fibril Organization Protein Methylation Response To Temperature Stimulus Regulation Of Organelle Organization Regulation Of Cell Cycle Peptidyl-amino Acid Modification Clathrin Coat Disassembly Neuron Development MRNA Splicing, Via Spliceosome Serine Phosphorylation Of STAT Protein RNA Splicing, Via Transesterification Reactions Neuron Differentiation Protein Folding Response To Herbicide Protein Autoprocessing Regulation Of Mitochondrion Degradation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Histone H4-R3 Methylation RNA Splicing Histone H3-K4 Trimethylation Endothelial Cell Activation I-kappaB Phosphorylation Cellular Response To Interferon-beta Histone Modification Peptidyl-arginine N-methylation Methylation MRNA Processing Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Chaperone Mediated Protein Folding Requiring Cofactor Response To Interferon-beta Generation Of Neurons Forebrain Development Histone Arginine Methylation Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Refolding Peptidyl-arginine Methylation Neurogenesis Regulation Of Histone H3-K4 Methylation Cellular Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway	Positive Regulation Of Fibroblast Proliferation Regulation Of Fibroblast Proliferation Positive Regulation Of DNA Damage Checkpoint Cell Dedifferentiation Regulation Of Cell Cycle G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Rhythmic Process Positive Regulation Of Gene Expression Glucocorticoid Receptor Signaling Pathway Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Cellular Senescence Positive Regulation Of Cell Size Positive Regulation Of Cell Cycle Checkpoint Regulation Of Gene Expression Cell Division Regulation Of DNA Damage Checkpoint Negative Regulation Of Cell Cycle Posttranscriptional Regulation Of Gene Expression Hematopoietic Stem Cell Differentiation Negative Regulation Of Cell Aging Regulation Of Cell Cycle Process Dentate Gyrus Development Type B Pancreatic Cell Development Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Astrocyte Development Positive Regulation Of Cell Death Type B Pancreatic Cell Differentiation Negative Regulation Of Cell Cycle Arrest Lateral Ventricle Development Enteroendocrine Cell Differentiation Hemopoiesis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Cellular Senescence Response To Lead Ion Mitochondrial Fission Labyrinthine Layer Blood Vessel Development Response To Hyperoxia Mitotic Cell Cycle Process Glandular Epithelial Cell Development Regulation Of Cellular Response To Heat Immune System Development Response To Testosterone
Tagcloud ?		11s acetylation atm atr axis chk2 clarify contributes damage dbc1 ddr deleted depends inactivation indeed kiaa1967 link modification modifications preventing proteasome reduces reggamma ser247 sirt1 spreading thr454 transducer upon
Tagcloud (Difference) ?		11s acetylation atm atr axis chk2 clarify contributes damage dbc1 ddr deleted depends inactivation indeed kiaa1967 link modification modifications preventing proteasome reduces reggamma ser247 sirt1 spreading thr454 transducer upon
Tagcloud (Intersection) ?