DENND1A and ARF5

Number of citations of the paper that reports this interaction (PubMedID 33443570)
75

Data Source:
BioGRID (pull down)

		DENND1A	ARF5
Description		DENN domain containing 1A	ARF GTPase 5
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Clathrin-coated Vesicle Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Presynaptic Membrane Cell Projection Synapse	Cytoplasm Golgi Apparatus Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Lipid Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Phosphate Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Endocytosis Protein Transport Endocytic Recycling Regulation Of Rab Protein Signal Transduction	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Vesicle-mediated Transport
Pathways		RAB GEFs exchange GTP for GDP on RABs	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145) Body mass index ( 26426971) Body mass index in non-asthmatics ( 23517042) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Depression ( 29700475) Feeling nervous ( 29500382) Femur bone mineral density x serum urate levels interaction ( 34046847) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Major depressive disorder ( 27479909) Myopia (pathological) ( 23049088) Personality dimensions ( 20691247) Polycystic ovary syndrome ( 21151128 30566500 26416764 26284813) Polycystic ovary syndrome (adjusted for age and BMI) ( 34791234) Polycystic ovary syndrome (adjusted for age) ( 34791234) Rheumatoid arthritis ( 30891314) Self-reported risk-taking behaviour ( 30271922) Suffering from nerves ( 29500382) Tea consumption ( 31046077) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Waist circumference ( 23966867)	Type 2 diabetes ( 23532257)
Interacting Genes		4 interacting genes: ARF1 ARF4 ARF5 PCM1	17 interacting genes: ACY3 AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 DANCR DENND1A DENND1B DTX3 ERBB2 GGA1 GORAB IKBKG PIP5K1A RAB11FIP3 SNCA
Entrez ID		57706	381
HPRD ID		17221	00055
Ensembl ID		ENSG00000119522	ENSG00000004059
Uniprot IDs		A0A0A0MS48 Q8TEH3 Q9HCG4	A4D0Z3 P84085
PDB IDs		6EKK	2B6H
Enriched GO Terms of Interacting Partners?		GTPase Activity Cellular Localization GTP Binding Establishment Of Localization In Cell Intracellular Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intracellular Protein Localization Intracellular Protein Transport Mitotic Cleavage Furrow Ingression Cleavage Furrow Ingression Phospholipase D Activator Activity Protein-containing Complex Localization To Centriolar Satellite Plasma Membrane Bounded Cell Projection Organization Protein Transport Cell Projection Organization Interkinetic Nuclear Migration Vesicle-mediated Transport Establishment Of Protein Localization NAD+-protein-arginine ADP-ribosyltransferase Activity Cilium Assembly Golgi Vesicle Transport Intraciliary Transport Involved In Cilium Assembly Golgi Apparatus Cilium Organization Plasma Membrane Bounded Cell Projection Assembly Microtubule Anchoring At Centrosome Cell Projection Assembly Microtubule Anchoring At Microtubule Organizing Center Nucleotide Binding Intracellular Copper Ion Homeostasis Long-term Synaptic Depression Apical Protein Localization Dendritic Spine Development Regulation Of Protein Complex Stability Copper Ion Homeostasis Pericentriolar Material Neuronal Stem Cell Population Maintenance Mitotic Cytokinetic Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Extracellular Exosome Microtubule Anchoring Protein Localization To Centrosome Nuclear Migration Nucleus Localization Non-motile Cilium Golgi Membrane Dendritic Spine Organization Epidermal Growth Factor Receptor Binding Protein Localization To Organelle Ciliary Transition Zone	Cellular Localization Establishment Of Localization In Cell Localization Within Membrane Trans-Golgi Network Membrane Intracellular Protein Localization Golgi Apparatus Clathrin-coated Vesicle Membrane Protein Transport Vesicle-mediated Transport To The Plasma Membrane Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Cytosol Clathrin Adaptor Complex Endocytic Recycling Protein Localization To Cell Periphery Protein Domain Specific Binding Melanosome Assembly Endosomal Transport Establishment Of Vesicle Localization GTP-dependent Protein Binding Small GTPase Binding Intracellular Protein Transport Platelet Dense Granule Organization Protein Localization To Membrane Vesicle Localization Phospholipid Binding Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Early Endosome Phosphatidylinositol Phosphate Binding Membrane Coat Phosphatidylinositol-4-phosphate Binding Protein Localization To Cell Surface Regulation Of Actin Nucleation Synaptic Vesicle Transport Golgi To Plasma Membrane Protein Transport Melanosome Organization Pigment Granule Organization Cytoplasmic Vesicle Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity Negative Regulation Of Retrograde Transport, Endosome To Golgi
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?