FABP3 and VPS28

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		FABP3	VPS28
Gene Name		fatty acid binding protein 3, muscle and heart	vacuolar protein sorting 28 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytosol Sarcoplasm Extracellular Vesicular Exosome	ESCRT I Complex Cytoplasm Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Long-chain Fatty Acid Transporter Activity Protein Binding Cytoskeletal Protein Binding Long-chain Fatty Acid Binding Icosatetraenoic Acid Binding Oleic Acid Binding	Protein Binding Protein Complex Binding
	Biological Process	Fatty Acid Metabolic Process Negative Regulation Of Cell Proliferation Response To Insulin Response To Drug Cholesterol Homeostasis Long-chain Fatty Acid Import Regulation Of Fatty Acid Oxidation Phospholipid Homeostasis Response To Fatty Acid Positive Regulation Of Phospholipid Biosynthetic Process	Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Negative Regulation Of Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Intracellular Transport Of Virus
Pathways			Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Alcohol dependence ( 23455491)
Protein-Protein Interactions		4 interactors: KIAA1598 NUP62 TNNI3K VPS28	27 interactors: ASF1A BLZF1 CARD9 CBX5 FABP3 FAM154A GABARAP GLCCI1 GOLGA2 INCA1 MBIP PDCD6IP PNMA5 RASSF5 SKIL SMN2 TCF12 TCF4 TRIM27 TRIM54 TSG101 UBA52 USHBP1 VPS37A VPS37B VPS37C VPS52
Entrez ID		2170	51160
HPRD ID		00613	11675
Ensembl ID			ENSG00000160948
Uniprot IDs		P05413	Q548N1 Q9UK41
PDB IDs		1G5W 1HMR 1HMS 1HMT 2HMB 3RSW
Enriched GO Terms of Interacting Partners?		Viral Life Cycle Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Viral Protein Processing Viral Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Targeting To Vacuole Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of ERBB Signaling Pathway Establishment Of Protein Localization To Vacuole Intracellular Transport Of Virus Cytoplasmic Transport Mitotic Nuclear Envelope Disassembly Regulation Of Establishment Of Cell Polarity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Establishment Or Maintenance Of Cell Polarity Nuclear Envelope Disassembly Negative Regulation Of ERBB Signaling Pathway	Virion Assembly Viral Protein Processing Intracellular Transport Of Virus Viral Life Cycle Protein Transport Endosomal Transport Establishment Of Protein Localization Viral Process Protein Localization Membrane Organization Protein Processing Intracellular Transport Regulation Of Extracellular Vesicular Exosome Assembly Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Cell Cycle Establishment Of Localization In Cell Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Gene Expression Negative Regulation Of Transferase Activity Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Cell Death Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Localization Cell Cycle Arrest Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Protein Trimerization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Embryonic Digestive Tract Development Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Negative Regulation Of Protein Kinase Activity DNA-templated Transcription, Initiation Transport Negative Regulation Of Gene Expression Muscle Structure Development Negative Regulation Of Biosynthetic Process Negative Regulation Of Kinase Activity Cell Cycle Positive Regulation Of Lipid Biosynthetic Process Glycogen Metabolic Process
Tagcloud ?		ascl2 c4b dab2ip dlk1 eya4 fzd9 gas7 hdac9 hoxa11 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 rbp1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1	advancement cd connected counterscreen crohn encodes endosomal immortalized initiating irrespective multidomain nod2 proinflammatory regulators relapsing resource revealing reveals screen secretion sensor sorting strongest subnetworks tnfalpha usp8 validate valuable vesicle
Tagcloud (Difference) ?		ascl2 c4b dab2ip dlk1 eya4 fzd9 gas7 hdac9 hoxa11 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 rbp1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1	advancement cd connected counterscreen crohn encodes endosomal immortalized initiating irrespective multidomain nod2 proinflammatory regulators relapsing resource revealing reveals screen secretion sensor sorting strongest subnetworks tnfalpha usp8 validate valuable vesicle
Tagcloud (Intersection) ?