FANCM and APITD1

Number of citations of the paper that reports this interaction (PMID 20347428)
54

Data Source:
BioGRID (pull down)

		FANCM	APITD1
Gene Name		Fanconi anemia, complementation group M	apoptosis-inducing, TAF9-like domain 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Condensed Chromosome Kinetochore Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex FANCM-MHF Complex
	Molecular Function	DNA Binding Chromatin Binding Helicase Activity Nuclease Activity Protein Binding ATP Binding	DNA Binding Chromatin Binding Double-stranded DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Resolution Of Meiotic Recombination Intermediates DNA Repair Replication Fork Processing Nucleic Acid Phosphodiester Bond Hydrolysis	Mitotic Cell Cycle Resolution Of Meiotic Recombination Intermediates DNA Repair Nucleosome Assembly Cellular Response To DNA Damage Stimulus Mitotic Nuclear Division Replication Fork Processing Positive Regulation Of Protein Ubiquitination CENP-A Containing Nucleosome Assembly Cell Division
Pathways		Fanconi Anemia pathway	Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APITD1 APP C19orf40 ECT2 EME2 STRA13 SUMO1 TRIM27	4 interactors: APP FANCM HOMEZ STRA13
Entrez ID		57697	378708
HPRD ID		13876	18797
Ensembl ID		ENSG00000187790
Uniprot IDs		B2RTQ9 Q8IYD8	Q8N2Z9
PDB IDs		4BXO 4DAY 4DRB 4E45	4DRA 4DRB 4E44 4E45
Enriched GO Terms of Interacting Partners?		Response To Stress DNA Repair Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Cellular Protein Metabolic Process Resolution Of Meiotic Recombination Intermediates DNA Metabolic Process Replication Fork Processing Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Chromosome Separation CENP-A Containing Nucleosome Assembly Cellular Response To Stimulus DNA Recombination Histone Exchange DNA Replication-independent Nucleosome Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Reciprocal Meiotic Recombination Centromere Complex Assembly Cellular Nitrogen Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Response To Stimulus Protein Complex Assembly Reproduction ATP-dependent Chromatin Remodeling Nitrogen Compound Metabolic Process Cell Division Meiotic Chromosome Segregation Response To Radiation Meiosis I DNA-dependent DNA Replication Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleosome Assembly Chromatin Assembly Positive Regulation Of Protein Ubiquitination Collateral Sprouting In Absence Of Injury Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly PML Body Organization Meiotic Nuclear Division Positive Regulation Of Protein Complex Assembly Regulation Of Protein Kinase Activity	Resolution Of Meiotic Recombination Intermediates Replication Fork Processing Chromosome Separation Reciprocal Meiotic Recombination Meiotic Chromosome Segregation Meiosis I DNA-dependent DNA Replication Meiotic Nuclear Division Synaptic Growth At Neuromuscular Junction Reproduction Meiotic Cell Cycle Collateral Sprouting In Absence Of Injury Chromosome Segregation DNA Recombination Collateral Sprouting Axon Midline Choice Point Recognition DNA Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Response To Light Stimulus Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Response To Radiation Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Kinetochore Assembly DNA Repair Entrainment Of Circadian Clock By Photoperiod Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Photoperiodism Entrainment Of Circadian Clock CENP-A Containing Nucleosome Assembly Kinetochore Organization Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Histone Exchange DNA Replication-independent Nucleosome Assembly Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Polyadenylation Neuron Recognition
Tagcloud ?		anemia arise atm deficiency encoding failure fanconi fertility germ hypogonadism includes instability maintenance males meiotic neonates overlaid partially pgcs phenotypes primordial progressive propagate propagation repair sexes testicular true
Tagcloud (Difference) ?		anemia arise atm deficiency encoding failure fanconi fertility germ hypogonadism includes instability maintenance males meiotic neonates overlaid partially pgcs phenotypes primordial progressive propagate propagation repair sexes testicular true
Tagcloud (Intersection) ?