STRA13 and NKX3-1

Number of citations of the paper that reports this interaction (PMID 18816836)
2

Data Source:
BioGRID (two hybrid)

		STRA13	NKX3-1
Gene Name		stimulated by retinoic acid 13	NK3 homeobox 1
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Intracellular Nucleus
	Molecular Function	DNA Binding Double-stranded DNA Binding Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor Activity Core Promoter Binding Sequence-specific DNA Binding Transcription Factor Activity Androgen Receptor Activity Protein Binding Transcription Factor Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Estrogen Receptor Activity Protein Kinase Activator Activity Estrogen Receptor Binding Histone Deacetylase Binding Sequence-specific DNA Binding Protein Self-association Transcription Regulatory Region DNA Binding MADS Box Domain Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates DNA Repair Nucleosome Assembly Mitotic Nuclear Division Replication Fork Processing Positive Regulation Of Protein Ubiquitination CENP-A Containing Nucleosome Assembly Cell Division Kinetochore Assembly	Metanephros Development Somitogenesis Positive Regulation Of Protein Phosphorylation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Multicellular Organismal Development Salivary Gland Development Heart Development Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Male Gonad Development Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Death Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Androgen Receptor Signaling Pathway Response To Testosterone Cellular Response To Drug Dorsal Aorta Development Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Steroid Hormone Mediated Signaling Pathway Protein Kinase B Signaling Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Branching Morphogenesis Of An Epithelial Tube Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Cell Division Pharyngeal System Development Branching Involved In Prostate Gland Morphogenesis Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Steroid Hormone Stimulus Cellular Response To Hypoxia Mitotic Cell Cycle Arrest Negative Regulation Of Estrogen Receptor Binding Positive Regulation Of Androgen Secretion Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Chromosome Maintenance Nucleosome assembly Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APITD1 FANCM NKX3-1 REL TP53 TRIM54 UBE2I	32 interactors: AEN CCT7 CHPF CKAP4 FEM1B HIPK2 HMG20B HNRNPA0 HSP90B1 LMCD1 MAN2B1 MNAT1 ND4 PEBP1 PTMS RABL6 RARG RPL37A RPSA SP1 SP2 SP3 SP4 SP5 SPDEF SRF STMN3 STRA13 TEX264 TOPORS TPT1 WDR77
Entrez ID		201254	4824
HPRD ID		18121	03620
Ensembl ID		ENSG00000169689	ENSG00000167034
Uniprot IDs		A8MT69 J3QRS1	Q99801
PDB IDs		4DRA 4DRB 4E44 4E45	2L9R
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Resolution Of Meiotic Recombination Intermediates Mitotic Cell Cycle Arrest Replication Fork Processing Cell Cycle Chromosome Separation Chromosome Segregation Reciprocal Meiotic Recombination Cellular Response To Drug Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Metabolic Process Meiotic Chromosome Segregation Somitogenesis Positive Regulation Of Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Biosynthetic Process Somite Development Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Meiosis I DNA-dependent DNA Replication Cellular Response To Oxygen Levels Segmentation Cellular Response To Stress DNA Repair Negative Regulation Of Macromitophagy Positive Regulation Of Androgen Secretion Oligodendrocyte Apoptotic Process Chromatin Assembly Mitotic Cell Cycle Process Cell Cycle Arrest Chromatin Assembly Or Disassembly Negative Regulation Of Helicase Activity Negative Regulation Of Estrogen Receptor Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Meiotic Nuclear Division Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Signal Transduction DNA Packaging Cellular Macromolecule Biosynthetic Process Cellular Response To DNA Damage Stimulus Macromolecule Biosynthetic Process	Nucleobase-containing Compound Metabolic Process RNA Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Embryonic Eye Morphogenesis Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Embryonic Camera-type Eye Development Regulation Of Transcription From RNA Polymerase II Promoter Eye Morphogenesis Biosynthetic Process Megakaryocyte Differentiation Trophectodermal Cell Differentiation Camera-type Eye Development Eye Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Erythrocyte Differentiation Erythrocyte Homeostasis Blastocyst Formation Embryonic Camera-type Eye Morphogenesis Camera-type Eye Morphogenesis Organ Morphogenesis Myeloid Cell Homeostasis Organ Development Embryonic Organ Development Glandular Epithelial Cell Differentiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Embryonic Organ Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Embryonic Process Involved In Female Pregnancy Sensory Organ Development Prostate Gland Development Regulation Of RNA Metabolic Process Enucleate Erythrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Tissue Development System Development Homeostasis Of Number Of Cells
Tagcloud ?		advance angiographically angiography arteriovenous auto autoantibodies autoimmunity bioinformatics camk2a carotid cd79a cerebrovascular collateral ctnnb1 custom devastating edil3 efna3 elisas fragile gps1 interpolating malformation mmd moyamoya occlusion ror1 stenosis supraclinoid
Tagcloud (Difference) ?		advance angiographically angiography arteriovenous auto autoantibodies autoimmunity bioinformatics camk2a carotid cd79a cerebrovascular collateral ctnnb1 custom devastating edil3 efna3 elisas fragile gps1 interpolating malformation mmd moyamoya occlusion ror1 stenosis supraclinoid
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