CEP152

Description		centrosomal protein 152
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GO Annotations	Cellular Component	Pericentriolar Material Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Nuclear Body Ciliary Basal Body Deuterosome Procentriole Procentriole Replication Complex
	Molecular Function	Protein Binding Protein Kinase Binding
	Biological Process	Centriole Replication Cell Projection Organization Centrosome Duplication De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Seckel syndrome
GWAS		Diastolic blood pressure ( 30578418) Insomnia ( 23728906) Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: CIP2A EPB41L3
Entrez ID		22995
HPRD ID		16778
Ensembl ID		ENSG00000103995
Uniprot IDs		O94986 Q3B7A2
PDB IDs		4N7V 6CSU 6CSV
Enriched GO Terms of Interacting Partners?		Protein Localization To Paranode Region Of Axon Ciliary Basal Body Cytoskeletal Protein-membrane Anchor Activity Protein Localization To Juxtaparanode Region Of Axon Broken Chromosome Clustering Paranodal Junction Assembly Paranode Region Of Axon Juxtaparanode Region Of Axon Axolemma Protein Localization To Axon Myelin Maintenance Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Cortical Actin Cytoskeleton Organization Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Cortical Cytoskeleton Organization Protein Phosphatase Inhibitor Activity Cytoskeletal Protein Binding
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