POGK and GOLGB1

Data Source: HiPPIP (Novel)

		POGK	GOLGB1
Name		pogo transposable element derived with KRAB domain	golgin B1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Cytosol Membrane
	Molecular Function	Nucleic Acid Binding DNA Binding Protein Binding	RNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription	Regulation Of DNA-templated Transcription Golgi Organization Protein Localization To Pericentriolar Material
Pathways		None	Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins
GWAS		Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (min-P) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Cortical thickness (MOSTest) ( 32665545 ) Post-traumatic stress disorder ( 25456346 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 )	Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Mean reticulocyte volume ( 32888494 )
Novel Interactors		1 novel interactors: GOLGB1	2 novel interactors: INTS5 POGK
Interacting Genes		2 interacting genes: APP UCHL3	19 interacting genes: ACBD3 ADRB2 BRMS1 CAV2 CEP126 ECPAS ITSN2 MAPK7 NDUFA1 NOD2 PFN2 RNF10 SKIL SLC2A3 SREBF2 UBE2I USO1 USP7 VTI1B
Entrez ID		57645	2804
HPRD ID		17872	03933
Ensembl ID		ENSG00000143157	ENSG00000173230
Uniprot IDs		B4DF62 Q9P215	A0A8J9C4H3 E7EU81 Q14789
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Golgi Apparatus Protein Localization To Pericentriolar Material Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway DeNEDDylase Activity Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle	PML Body Vesicle Docking ER To Golgi Transport Vesicle Membrane Vesicle Fusion With Golgi Apparatus Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Cellular Response To Laminar Fluid Shear Stress Organelle Membrane Fusion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Laminar Fluid Shear Stress Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Temperature Homeostasis Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of RNA Metabolic Process Positive Regulation Of Autophagy Receptor-mediated Endocytosis Regulation Of Autophagy Positive Regulation Of Mini Excitatory Postsynaptic Potential Golgi Apparatus Cytoplasm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Organelle Fusion Membrane Fusion Cellular Response To Fluid Shear Stress Response To Fluid Shear Stress SUMO Conjugating Enzyme Activity Golgi Vesicle Docking Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Mitophagy