EP400 and TRRAP

Number of citations of the paper that reports this interaction (PubMedID 11509179)
0

Data Source:
HPRD (in vitro, in vivo)

		EP400	TRRAP
Description		E1A binding protein p400	transformation/transcription domain associated protein
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GO Annotations	Cellular Component	Nucleosome Swr1 Complex Nucleus Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex	SAGA Complex Nucleosome Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Nucleotide Binding DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity Protein Antigen Binding	Transcription Coregulator Activity Protein Binding Kinase Activity
	Biological Process	DNA Repair Chromatin Organization Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	Regulation Of DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Regulation Of Cellular Response To Stress DNA Repair-dependent Chromatin Remodeling Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones	Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 27863252 28957414 32888494)	Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		15 interacting genes: ALAS1 ATM BRD8 CEBPA KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT	21 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CDC42 CEBPA CTNNB1 E2F1 E2F4 EP400 ESR1 HSF1 KAT2A MAX MRGBP MYC NANOG PYGO2 SKP1 TCF3
Entrez ID		57634	8295
HPRD ID		09378	04310
Ensembl ID		ENSG00000183495	ENSG00000196367
Uniprot IDs		Q96L91	H0Y4W2 Q9Y4A5
PDB IDs		8QR1 8QRI 8XVG 8XVT 8XVV 9C47 9C57 9C62 9C6N	7KTR 8H7G 8QRI 8XVG 8XVV 9C47
Enriched GO Terms of Interacting Partners?		Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of DNA Recombination Swr1 Complex Nucleoplasm Positive Regulation Of DNA Recombination Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair NuA4 Histone Acetyltransferase Complex Regulation Of DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Positive Regulation Of DNA Repair Regulation Of Cell Cycle Cellular Response To Oxygen-containing Compound Response To Xenobiotic Stimulus Site Of Double-strand Break Nucleolus Positive Regulation Of Chromosome Organization Transcription By RNA Polymerase I Nucleosome Protein-containing Complex Binding Positive Regulation Of RNA Biosynthetic Process DNA Double-strand Break Processing Response To X-ray Cellular Response To Gamma Radiation Regulation Of Nucleobase-containing Compound Metabolic Process Recombinational Repair Reciprocal Meiotic Recombination Response To Ionizing Radiation Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA-templated Transcription Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Localization To Site Of Double-strand Break DNA Repair-dependent Chromatin Remodeling Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Signal Transduction By P53 Class Mediator Cellular Response To Radiation Intrinsic Apoptotic Signaling Pathway Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Response To Radiation DNA-binding Transcription Factor Binding Homologous Recombination Chromatin Organization Meiosis I	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Nucleoplasm Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of DNA Repair Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA Metabolic Process Chromatin Organization DNA-binding Transcription Factor Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Binding Regulation Of Cellular Response To Stress Euchromatin Regulation Of RNA Metabolic Process Protein-containing Complex Nucleus RNA Polymerase II Transcription Regulator Complex Chromatin Regulation Of Apoptotic Process NuA4 Histone Acetyltransferase Complex Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death DNA-binding Transcription Factor Activity Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle Negative Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Population Proliferation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Transcription Regulator Complex Transcription Cis-regulatory Region Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA Repair Regulation Of Double-strand Break Repair Cellular Response To Xenobiotic Stimulus RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
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