ARRDC3 and MORF4L1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ARRDC3	MORF4L1
Gene Name		arrestin domain containing 3	mortality factor 4 like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Plasma Membrane	Nucleoplasm Sin3 Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Beta-3 Adrenergic Receptor Binding	Chromatin Binding Protein Binding Protein N-terminus Binding
	Biological Process	Temperature Homeostasis Negative Regulation Of Heat Generation Skin Development Negative Regulation Of Multicellular Organismal Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Fat Pad Development Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Locomotion Involved In Locomotory Behavior	Double-strand Break Repair Via Homologous Recombination Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Breast cancer (prognosis) ( 23319801) Subcutaneous adipose tissue ( 22589738)	Coronary heart disease ( 21378988)
Protein-Protein Interactions		14 interactors: BAG3 DCUN1D1 HPGDS ITCH MAGI2 MORF4L1 NEDD4 OTUB2 PDCD6IP STAM2 TNFAIP3 TRIM42 UBE2E2 WWP1	35 interactors: APP ARRDC3 BEND7 CALM1 CAMK2B CEP57L1 FAM9B FXR2 GMCL1 GOLGA2 HINFP HIST3H3 HMBOX1 IKZF1 L3MBTL3 LZTS2 MEOX1 MRFAP1 MRFAP1L1 MRGBP MSL1 NAB2 NAV2 PBXIP1 PHF12 RACGAP1 RB1 REL TFCP2 THAP1 TNIP1 TNNT1 TRIM41 ZBTB10 ZBTB9
Entrez ID		57561	10933
HPRD ID		09810	09532
Ensembl ID		ENSG00000113369	ENSG00000185787
Uniprot IDs		Q96B67	B3KTM8 Q9UBU8
PDB IDs			2AQL 2EFI 2F5J 2F5K 2LKM
Enriched GO Terms of Interacting Partners?		Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Deubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Interaction With Host Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Establishment Of Protein Localization To Vacuole Cellular Protein Metabolic Process Proteolysis Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Viral Life Cycle Intracellular Receptor Signaling Pathway Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Signal Transduction Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Viral Entry Into Host Cell Entry Into Host Cell Protein Catabolic Process Negative Regulation Of Signaling Negative Regulation Of Type I Interferon Production Cellular Response To Stimulus Protein Metabolic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of CD40 Signaling Pathway Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Protein Modification Process Negative Regulation Of Leukocyte Proliferation Cellular Macromolecule Catabolic Process Regulation Of Defense Response To Virus Regulation Of Protein Catabolic Process Tolerance Induction To Lipopolysaccharide Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Osteoclast Proliferation Planar Cell Polarity Pathway Involved In Axis Elongation Regulation Of Cell Cycle Negative Regulation Of Intracellular Signal Transduction Apoptotic Process Protein Deubiquitination	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Gene Expression RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Spindle Midzone Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Transcription, DNA-templated Cell Cycle Immune System Process Multicellular Organismal Development Regulation Of Cell Division Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cell Division Neuron Maturation Cell Maturation Chromatin Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Neutrophil Differentiation Cytokinesis, Initiation Of Separation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Tagcloud ?		adrenergic arrestin arrestins basic beta2 beta2ar capable conformations consists crystal crystallization downregulation electropositive highlights ions ligases lobe lobed motifs nedd4 parallels patch portion ppxy ppyx recruit situation tail thought	aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly
Tagcloud (Difference) ?		adrenergic arrestin arrestins basic beta2 beta2ar capable conformations consists crystal crystallization downregulation electropositive highlights ions lobe lobed motifs nedd4 parallels patch portion ppxy ppyx recruit situation tail thought	aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly
Tagcloud (Intersection) ?		ligases