ZNF346 and MIR9-3

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		ZNF346	MIR9-3
Description		zinc finger protein 346	microRNA 9-3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	RISC Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Double-stranded RNA Binding Protein Binding Zinc Ion Binding Enzyme Binding MiRNA Binding Metal Ion Binding
	Biological Process		MiRNA-mediated Post-transcriptional Gene Silencing
Pathways
Drugs
Diseases
GWAS		Height ( 28552196 31562340) Type 2 diabetes ( 30718926) Uterine fibroids ( 30194396 31649266) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Schizophrenia ( 28991256 30285260)
Interacting Genes		67 interacting genes: ADARB1 ANKHD1 EIF2AK2 ILF3 LNX1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR141 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18B MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR214 MIR221 MIR222 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A2 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I NKRF RNF10 RNF8 STRBP TARBP2 XPO5	66 interacting genes: ADARB1 APOBEC3B CRTAP DARS1 DDX1 DDX21 DDX3X EIF2AK2 EPRS1 ERAL1 FAM98A FIP1L1 FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LRPPRC MARS1 MATR3 MSI2 NONO P3H1 PDCD11 PRMT1 PTBP1 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SF3B1 SF3B3 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2B UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346 ZNF385A
Entrez ID		23567	407051
HPRD ID		05606
Ensembl ID		ENSG00000113761	ENSG00000284329
Uniprot IDs		B7Z4J8 B7Z4N4 D6RJ07 Q9UL40
PDB IDs		2MKD 2MKN
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Metabolic Process Extracellular Vesicle Negative Regulation Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Regulation Of Macromolecule Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cytokine Production Negative Regulation Of Cell Migration Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of MRNA Stability Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of RNA Stability Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Endothelial Cell Migration Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Signal Transduction Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Cell Migration Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cytokine Production	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Ribonucleoprotein Complex Macromolecule Metabolic Process MRNA Binding Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleus Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Catalytic Step 2 Spliceosome Spliceosomal Complex Negative Regulation Of MRNA Catabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Primary Metabolic Process MiRNA Binding Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Negative Regulation Of RNA Catabolic Process TRNA Aminoacylation MRNA Stabilization Regulation Of MRNA Processing Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process RNA Stabilization Regulation Of Metabolic Process Cytoplasmic Stress Granule Negative Regulation Of Macromolecule Metabolic Process TRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Alternative MRNA Splicing, Via Spliceosome CRD-mediated MRNA Stabilization Regulation Of RNA Stability Negative Regulation Of Metabolic Process Ligase Activity Negative Regulation Of Translation
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