MFSD3 and DPAGT1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MFSD3	DPAGT1
Gene Name		major facilitator superfamily domain containing 3	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Solute:proton Symporter Activity	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity Phospho-N-acetylmuramoyl-pentapeptide-transferase Activity Transferase Activity, Transferring Glycosyl Groups
	Biological Process	Transport Proton Transport Transmembrane Transport	Polysaccharide Biosynthetic Process UDP-N-acetylglucosamine Metabolic Process Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Dolichol Biosynthetic Process Post-translational Protein Modification Cellular Protein Metabolic Process Protein Oligomerization
Pathways			Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Defective ALG11 causes ALG11-CDG (CDG-1p)
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APPBP2 DPAGT1 MDFI PCDHGC3	2 interactors: LSM8 MFSD3
Entrez ID		113655	1798
HPRD ID		14003	01879
Ensembl ID		ENSG00000167700	ENSG00000172269
Uniprot IDs		Q96ES6	E7EW40 Q9H3H5
PDB IDs
Enriched GO Terms of Interacting Partners?		Dolichol Biosynthetic Process Dolichol Metabolic Process
Tagcloud ?			acetylcholine alg13 alg14 alg2 alg2p analogy asparagine catalyses cholinesterase committed concentrated congenital endplates exome fatigable girdle glycosylation inherited kinships mannosyltransferase multiglycosyltransferase multisystem myasthenic neuromuscular synapse underscores val68gly weakness wider
Tagcloud (Difference) ?			acetylcholine alg13 alg14 alg2 alg2p analogy asparagine catalyses cholinesterase committed concentrated congenital endplates exome fatigable girdle glycosylation inherited kinships mannosyltransferase multiglycosyltransferase multisystem myasthenic neuromuscular synapse underscores val68gly weakness wider
Tagcloud (Intersection) ?