SLC33A2 and DPAGT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SLC33A2	DPAGT1
Description		solute carrier family 33 member 2	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Transmembrane Transporter Activity	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Identical Protein Binding Metal Ion Binding
	Biological Process	Transmembrane Transport	Protein Glycosylation Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process
Pathways			Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective DPAGT1 causes CDG-1j, CMSTA2
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS			Estimated glomerular filtration rate ( 31152163) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		10 interacting genes: APPBP2 AQP6 DPAGT1 KRTAP10-6 MDFI MMGT1 PCDHGC3 PTAFR SLC7A8 UBE2J1	2 interacting genes: LSM8 SLC33A2
Entrez ID		113655	1798
HPRD ID		14003	01879
Ensembl ID		ENSG00000167700	ENSG00000172269
Uniprot IDs		Q96ES6	A0A804HI18 A0A804HKZ3 Q9H3H5
PDB IDs			5LEV 5O5E 6BW5 6BW6 6FM9 6FWZ 6JQ3
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Monoatomic Anion Channel Activity Nitrate Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Ammonium Transmembrane Transport Ammonium Channel Activity Nitrate Transmembrane Transport Renal Water Transport Cytoplasmic Vesicle Membrane Carbon Dioxide Transmembrane Transport UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Glycoprotein Biosynthetic Process Protein N-linked Glycosylation Platelet Activating Factor Receptor Activity G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Activity Inositol Trisphosphate Metabolic Process Lipopolysaccharide Immune Receptor Activity L-alanine Transport Tryptophan Transport Branched-chain Amino Acid Transport Proline Transmembrane Transport Aromatic Amino Acid Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity L-leucine Transport L-leucine Import Across Plasma Membrane Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-alanine Import Across Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Valine Transport Negative Regulation Of Protein Exit From Endoplasmic Reticulum Hrd1p Ubiquitin Ligase Complex Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Inorganic Cation Transmembrane Transporter Activity Cobalt Ion Transmembrane Transporter Activity Cobalt Ion Transport Ferrous Iron Transmembrane Transporter Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Organic Cation Transmembrane Transporter Activity Thyroid Hormone Transport
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