PSMD9 and CSH1

Number of citations of the paper that reports this interaction (PubMedID 25009770)
72

Data Source:
BioGRID (unspecified method)

		PSMD9	CSH1
Description		proteasome 26S subunit, non-ATPase 9	chorionic somatomammotropin hormone 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Proteasome Regulatory Particle Proteasome Regulatory Particle, Base Subcomplex	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Endomembrane System Endosome Lumen Vesicle
	Molecular Function	Transcription Coactivator Activity Protein Binding BHLH Transcription Factor Binding	Growth Hormone Receptor Binding Hormone Activity Protein Binding Growth Factor Activity Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Insulin Secretion Positive Regulation Of DNA-templated Transcription Negative Regulation Of Insulin Secretion Proteasome Regulatory Particle Assembly	Response To Nutrient Levels Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Animal Organ Development Growth Hormone Receptor Signaling Pathway
Pathways		Proteasome assembly	Prolactin receptor signaling Prolactin receptor signaling Growth hormone receptor signaling
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494) Mean platelet volume ( 24026423) Red blood cell count ( 32888494) Serum metabolite levels ( 33031748) Urinary metabolites (H-NMR features) ( 24586186)	Height ( 23563607 25429064 31562340)
Interacting Genes		21 interacting genes: AHCYL1 BANP BRCA1 CCDC136 CEP85L CKS1B CSH1 ELSPBP1 GH1 HNRNPA1 MEOX2 NCKIPSD PSMC6 RIN3 SKP2 TCF3 TNIP2 TRAF2 TRIM39 TRIM42 YY1	7 interacting genes: PRLR PSMD9 PTPN12 SGTB SMAD2 SMAD4 SMAD9
Entrez ID		5715	1442
HPRD ID		04394	08350
Ensembl ID		ENSG00000110801	ENSG00000136488
Uniprot IDs		O00233	A8K6C2 P0DML2
PDB IDs			1Z7C
Enriched GO Terms of Interacting Partners?		Growth Hormone Receptor Binding Immunoglobulin V(D)J Recombination CD40 Signaling Pathway Mitogen-activated Protein Kinase Kinase Kinase Binding V(D)J Recombination Positive Regulation Of DNA Metabolic Process Endosome Lumen Growth Hormone Receptor Signaling Pathway	Heteromeric SMAD Protein Complex SMAD Protein Complex I-SMAD Binding SMAD Protein Signal Transduction Activin Responsive Factor Complex Response To Growth Factor Developmental Growth Transforming Growth Factor Beta Receptor Signaling Pathway Secondary Palate Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway R-SMAD Binding Activin Receptor Signaling Pathway Embryonic Axis Specification Cellular Response To BMP Stimulus Endoderm Development Transcription Regulator Complex Cellular Response To Growth Factor Stimulus Gastrulation Organ Growth SMAD Binding Mesoderm Development Embryonic Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Intracellular Iron Ion Homeostasis Roof Of Mouth Development Epithelial Cell Differentiation Response To Transforming Growth Factor Beta Axis Specification Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis BMP Signaling Pathway Homomeric SMAD Protein Complex Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Prolactin Receptor Activity TRC Complex Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Regulation Of Hormone Levels Zygotic Specification Of Dorsal/ventral Axis Response To Glucose Ameboidal-type Cell Migration Paraxial Mesoderm Morphogenesis Osteoblast Differentiation Left Ventricular Cardiac Muscle Tissue Morphogenesis Metanephric Mesenchyme Morphogenesis Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity
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