CSH1

Description		chorionic somatomammotropin hormone 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Endomembrane System Endosome Lumen Vesicle
	Molecular Function	Growth Hormone Receptor Binding Hormone Activity Protein Binding Growth Factor Activity Metal Ion Binding
	Biological Process	Response To Nutrient Levels Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Animal Organ Development Growth Hormone Receptor Signaling Pathway
Pathways		Prolactin receptor signaling Prolactin receptor signaling Growth hormone receptor signaling
Drugs
Diseases
GWAS		Height ( 23563607 25429064 31562340)
Interacting Genes		7 interacting genes: PRLR PSMD9 PTPN12 SGTB SMAD2 SMAD4 SMAD9
Entrez ID		1442
HPRD ID		08350
Ensembl ID		ENSG00000136488
Uniprot IDs		A8K6C2 P0DML2
PDB IDs		1Z7C
Enriched GO Terms of Interacting Partners?		Heteromeric SMAD Protein Complex SMAD Protein Complex I-SMAD Binding SMAD Protein Signal Transduction Activin Responsive Factor Complex Response To Growth Factor Developmental Growth Transforming Growth Factor Beta Receptor Signaling Pathway Secondary Palate Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway R-SMAD Binding Activin Receptor Signaling Pathway Embryonic Axis Specification Cellular Response To BMP Stimulus Endoderm Development Transcription Regulator Complex Cellular Response To Growth Factor Stimulus Gastrulation Organ Growth SMAD Binding Mesoderm Development Embryonic Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Intracellular Iron Ion Homeostasis Roof Of Mouth Development Epithelial Cell Differentiation Response To Transforming Growth Factor Beta Axis Specification Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis BMP Signaling Pathway Homomeric SMAD Protein Complex Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Prolactin Receptor Activity TRC Complex Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Regulation Of Hormone Levels Zygotic Specification Of Dorsal/ventral Axis Response To Glucose Ameboidal-type Cell Migration Paraxial Mesoderm Morphogenesis Osteoblast Differentiation Left Ventricular Cardiac Muscle Tissue Morphogenesis Metanephric Mesenchyme Morphogenesis Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity
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