RTN4 and COL4A3BP

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RTN4	COL4A3BP
Gene Name		reticulon 4	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
Image
Gene Ontology Annotations	Cellular Component	Intracellular Nuclear Envelope Endoplasmic Reticulum Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Cell Projection Neuronal Cell Body Extracellular Vesicular Exosome	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Poly(A) RNA Binding	Protein Kinase Activity Protein Binding Ceramide Transporter Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding
	Biological Process	Angiogenesis Apoptotic Process Axonal Fasciculation Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of Cell Growth Regulation Of Cell Migration Negative Regulation Of Axon Extension Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Axonogenesis Negative Regulation Of Axonogenesis Cardiac Epithelial To Mesenchymal Transition Endoplasmic Reticulum Tubular Network Organization Regulation Of Branching Morphogenesis Of A Nerve	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Protein Phosphorylation Sphingolipid Metabolic Process Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Proliferation Sphingolipid Biosynthetic Process Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Small Molecule Metabolic Process Lipid Homeostasis Mitochondrion Morphogenesis
Pathways		Signalling by NGF Axonal growth inhibition (RHOA activation) p75NTR regulates axonogenesis p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS		Obesity (extreme) ( 19553259)	Quantitative traits ( 19197348)
Protein-Protein Interactions		34 interactors: ARL6IP1 BAIAP2 BCL2 BCL2L1 CLN8 CNTNAP1 COL4A3BP CRMP1 FXR2 HLA-DPB1 LAMA4 LRCH4 LRPAP1 MBP NAPA NR4A1 PLEKHF2 POT1 PRR13 RAB33A RPS27 RTN3 RTN4IP1 RTN4R SNX1 SNX15 SPG21 SYT16 TERF1 TUBA4A UQCRC1 UQCRC2 WWP1 ZFYVE21	10 interactors: ACTL8 ARL6IP1 CBS COL4A3 CSNK1G2 ITGB3BP POM121 RTN3 RTN4 TGM2
Entrez ID		57142	10087
HPRD ID		07259	05246
Ensembl ID		ENSG00000115310	ENSG00000113163
Uniprot IDs		Q9NQC3	Q9Y5P4
PDB IDs		2G31 2JV5	2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T
Enriched GO Terms of Interacting Partners?		Transport Establishment Of Localization In Cell Membrane Organization Cell Part Morphogenesis Intracellular Transport Negative Regulation Of Telomere Maintenance Via Telomerase Cellular Localization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Mitochondrial Membrane Organization Regulation Of Telomere Maintenance Via Telomerase Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Anoikis Regulation Of Telomerase Activity Neuromuscular Process Controlling Posture Regulation Of Anoikis Regulation Of Telomere Maintenance Immune Response-regulating Signaling Pathway RNA-dependent DNA Replication Regulation Of Autophagy Mitochondrion Morphogenesis Cell Morphogenesis Negative Regulation Of DNA Biosynthetic Process Vesicle-mediated Transport Immune Response-activating Cell Surface Receptor Signaling Pathway System Development Neuron Differentiation Nervous System Development Axonogenesis Release Of Cytochrome C From Mitochondria Regulation Of Cellular Component Organization Cell Projection Morphogenesis Telomere Maintenance Via Telomere Lengthening Antigen Receptor-mediated Signaling Pathway Generation Of Neurons Anatomical Structure Development Aging Axon Development Developmental Process Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Response To Alkaloid Regulation Of Mitochondrial Membrane Permeability Cell Morphogenesis Involved In Neuron Differentiation Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Membrane Permeability Neurogenesis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway	Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Organization Cysteine Biosynthetic Process From Serine Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Apoptotic Process Programmed Cell Death Cell Death Death Endomembrane System Organization Cell Surface Receptor Signaling Pathway Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Transsulfuration Endothelial Cell Apoptotic Process Regulation Of Branching Morphogenesis Of A Nerve Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death L-serine Catabolic Process Positive Regulation Of Cell Death Hydrogen Sulfide Metabolic Process Regulation Of Apoptotic Process Salivary Gland Cavitation Regulation Of Cell Death Cysteine Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Neurotrophin Signaling Pathway Homocysteine Metabolic Process
Tagcloud ?		advance caspase caspases cdd corrected crosstalk disrupted doi emerges extrinsic flice flip flipl impinging initiator juxtaposition localizes mams mechanistically mefs mitochondria morphology platforms publication restrict reticulon shaping spatially tethering
Tagcloud (Difference) ?		advance caspase caspases cdd corrected crosstalk disrupted doi emerges extrinsic flice flip flipl impinging initiator juxtaposition localizes mams mechanistically mefs mitochondria morphology platforms publication restrict reticulon shaping spatially tethering
Tagcloud (Intersection) ?