NUP107 and NUP214

Number of citations of the paper that reports this interaction (PMID 9166401)
27

Data Source:
HPRD (in vivo)

		NUP107	NUP214
Gene Name		nucleoporin 107kDa	nucleoporin 214kDa
Image
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Centrosome Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery	Nucleus Nuclear Pore Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleocytoplasmic Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore	Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Nuclear Pore Complex Assembly Transmembrane Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Regulation Of Cell Cycle Transmembrane Transport
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport HuR stabilizes mRNA M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Regulation of mRNA stability by proteins that bind AU-rich elements Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS		White blood cell count ( 20139978)
Protein-Protein Interactions		2 interactors: NUP133 NUP214	19 interactors: APC CLEC4G DDX19B IPO5 NFX1 NUP107 NUP88 NUPL2 NXF1 NXF2 NXF3 SMAD2 SMAD3 SMAD4 TNPO1 XPO1 XPO5 XPOT ZFP36
Entrez ID		57122	8021
HPRD ID		06356	00258
Ensembl ID		ENSG00000111581	ENSG00000126883
Uniprot IDs		B4DZ67 P57740	P35658
PDB IDs		3CQC 3CQG 3I4R	2OIT 3FHC 3FMO 3FMP
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly MRNA Export From Nucleus Nuclear Envelope Organization Glucose Transport RNA Export From Nucleus Hexose Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export MRNA Transport Nucleus Organization Carbohydrate Transport RNA Transport RNA Localization Viral Life Cycle Pathogenesis Nucleocytoplasmic Transport Nuclear Transport Endomembrane System Organization Cytokine-mediated Signaling Pathway Viral Process Cellular Response To Cytokine Stimulus Nuclear Pore Organization Mitotic Cell Cycle Process Cytoplasmic Transport Response To Cytokine Mitotic Cell Cycle Membrane Organization Carbohydrate Metabolic Process Cell Cycle Process Paraxial Mesoderm Development Protein Export From Nucleus Cell Cycle Protein Transport Establishment Of Protein Localization Intracellular Transport Transmembrane Transport Cellular Response To Organic Substance Protein Localization Establishment Of Localization In Cell Small Molecule Metabolic Process Protein Import Into Nucleus Nuclear Import RNA Biosynthetic Process Cellular Localization Response To Organic Substance Mesoderm Development Protein Import Protein Localization To Nucleus	Nucleocytoplasmic Transport Nuclear Transport Nuclear Export RNA Transport RNA Localization MRNA Transport Cytoplasmic Transport RNA Export From Nucleus Viral Process Gene Expression MRNA Export From Nucleus Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Transport SMAD Protein Complex Assembly Establishment Of Protein Localization Gene Silencing By RNA Protein Localization Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing Positive Regulation Of Epithelial To Mesenchymal Transition Protein Export From Nucleus Gene Silencing By MiRNA Mitotic Nuclear Envelope Disassembly Transforming Growth Factor Beta Receptor Signaling Pathway Posttranscriptional Gene Silencing Nuclear Envelope Disassembly Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Envelope Organization Somatic Stem Cell Maintenance Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Hexose Transport Embryonic Pattern Specification
Tagcloud ?		apparatus brefeldin coat contributions copii defects differentiate digestive disrupt disrupted excessive facilitates lamination npc nucleo oligonucleotide organ organogenesis phenocopied pore pores retina retinal sec13 sec31a sec31b sq198 surprisingly traffic	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?		apparatus brefeldin coat contributions copii defects differentiate digestive disrupt disrupted excessive facilitates lamination npc nucleo oligonucleotide organ organogenesis phenocopied pore pores retina retinal sec13 sec31a sec31b sq198 surprisingly traffic	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?