SYNPR and FATE1

Number of citations of the paper that reports this interaction (PubMedID 29892012)
71

Data Source:
BioGRID (two hybrid)

		SYNPR	FATE1
Description		synaptoporin	fetal and adult testis expressed 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Synapse	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process		Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration
Pathways
Drugs
Diseases
GWAS		Autism ( 30675382) Congenital heart disease (inherited effect) ( 28468790) Congenital left-sided heart lesions ( 25138779) Idiopathic downbeat nystagmus ( 32157568) Lean body mass ( 28552196) Major depressive disorder ( 29317602)	Systemising ( 31508503)
Interacting Genes		11 interacting genes: ARLN CREB3 DOLK FATE1 GALNT15 GPR37L1 KTN1 PLPP6 SLC1A1 SMCO4 TRARG1	99 interacting genes: AGTRAP APOL3 AQP9 ASGR2 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 C1QL4 CALN1 CCDC70 CD302 CD79A CD83 CDC37 CERS4 CREB3L3 CSF2RA CTRL CXCR1 CXCR3 DCTN5 DNAJC30 EMD FAM177A1 FAM209A FRMD8 GIMAP5 GINM1 GOSR2 GPR25 HSD17B13 INPP5K KASH5 KCNS2 LMNA LNPEP LRRC25 MARCHF2 MARCHF3 MARCHF5 MARVELD2 MFF MOSPD3 MR1 NDUFB11 NRG4 NRSN1 OCLN OTOP2 PIN4 PKMYT1 PLP2 PRRG2 RBFA RIC3 RNF183 RPRM RTP2 SCAMP5 SEC22A SEC22C SEC23A SEC23B SLC38A1 SLC41A2 SLC7A1 SLC7A14 SMIM14 SNAP47 SSMEM1 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM179B TMEM201 TMEM74 TRAF2 TRAF3IP3 UBE2I UNC93B1 USHBP1 USP20 VSIG4 VSTM1 YIPF2 YIPF4 ZCCHC12 ZFPL1
Entrez ID		132204	89885
HPRD ID		15458	02346
Ensembl ID		ENSG00000163630	ENSG00000147378
Uniprot IDs		Q8TBG9	Q969F0
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum D-aspartate Transmembrane Transporter Activity Positive Regulation Of Deacetylase Activity Dolichol Kinase Activity Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Response To Anesthetic Conditioned Place Preference D-aspartate Import Across Plasma Membrane Cysteine Transmembrane Transport Intracellular Glutamate Homeostasis Vesicle-mediated Transport To The Plasma Membrane Cysteine Transport High-affinity L-glutamate Transmembrane Transporter Activity D-aspartate Transmembrane Transport Cysteine Transmembrane Transporter Activity Response To Ammonium Ion Cellular Response To Ammonium Ion Cellular Response To Mercury Ion Distal Dendrite Glutamate:sodium Symporter Activity Response To Bisphenol A Perisynaptic Space L-aspartate Import Across Plasma Membrane Cellular Response To Bisphenol A Prosaposin Receptor Activity Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation CCR1 Chemokine Receptor Binding Release From Viral Latency Terpenoid Metabolic Process Isoprenoid Metabolic Process Dolichol Phosphate Mannose Biosynthetic Process Dolichyl Monophosphate Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration Glucose Import In Response To Insulin Stimulus Lipid Phosphatase Activity Farnesyl Diphosphate Metabolic Process Geranyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Positive Regulation Of Neutrophil Activation	Membrane Protein Binding Endoplasmic Reticulum Nuclear Envelope Membrane Organization Endoplasmic Reticulum Membrane Cytoplasmic Vesicle Spindle Pole Centrosome Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Vesicle-mediated Transport Perinuclear Region Of Cytoplasm Positive Regulation Of Mitochondrial Fission COPII-coated Vesicle Budding
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