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PAK6 and RHOJ
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PAK6
RHOJ
Gene Name
p21 protein (Cdc42/Rac)-activated kinase 6
ras homolog family member J
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Receptor Signaling Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
GTPase Activity
GTP Binding
Biological Process
Mitotic Cell Cycle
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Apoptotic Process
Cytoskeleton Organization
Signal Transduction By Phosphorylation
Intracellular Signal Transduction
Small GTPase Mediated Signal Transduction
Rho Protein Signal Transduction
Metabolic Process
Regulation Of Cell Shape
Actin Cytoskeleton Organization
Regulation Of Small GTPase Mediated Signal Transduction
Retina Vasculature Morphogenesis In Camera-type Eye
Pathways
Axon guidance
Activation of Rac
Signaling by Robo receptor
Rho GTPase cycle
Signaling by Rho GTPases
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
13 interactors:
AKT1
APP
AR
CDC42
CDK1
ESR1
MAPK14
MDM2
NEK6
RHOJ
SEMA3B
SNX2
TPD52L1
21 interactors:
ACVR1
ADAMTSL4
BHLHE40
BLZF1
BMPR1B
CDC42
CDC42EP1
DOCK10
DOCK8
MEOX2
PAK1
PAK2
PAK6
PARD6B
SMAD2
SMAD4
SSX3
TGFBR1
TRIP10
WAS
WASL
Entrez ID
56924
57381
HPRD ID
06426
09632
Ensembl ID
ENSG00000137843
ENSG00000126785
Uniprot IDs
B3KYB0
G5E9R2
Q9NQU5
Q7Z513
Q9H4E5
PDB IDs
2C30
2ODB
4KS7
4KS8
Enriched GO Terms of Interacting Partners
?
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Transport
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Apoptotic Process
Positive Regulation Of Cell Cycle
Positive Regulation Of Gene Expression
Programmed Cell Death
Peptidyl-serine Phosphorylation
Cell Death
Death
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Proteolysis
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Cellular Metabolic Process
DNA Damage Checkpoint
Regulation Of Protein Kinase Activity
Regulation Of Protein Catabolic Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Intracellular Protein Transport
Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
ERBB Signaling Pathway
Regulation Of Mitotic Cell Cycle
Regulation Of Protein Localization
Regulation Of Kinase Activity
Regulation Of Phosphorylation
Regulation Of Cellular Protein Metabolic Process
Innate Immune Response
Regulation Of Intracellular Transport
Positive Regulation Of Cell Proliferation
Posttranscriptional Regulation Of Gene Expression
Positive Regulation Of Phosphorylation
Immune Response-regulating Signaling Pathway
Regulation Of Cell Cycle Process
Regulation Of Apoptotic Process
Positive Regulation Of Kinase Activity
Growth
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Macromolecule Biosynthetic Process
Neurotrophin Signaling Pathway
Positive Regulation Of Catalytic Activity
Cell Cycle Checkpoint
Regulation Of Cell Death
Signaling
Positive Regulation Of Cellular Biosynthetic Process
Intracellular Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Cell Morphogenesis Involved In Differentiation
Signal Transduction By Phosphorylation
Movement Of Cell Or Subcellular Component
Axonogenesis
Axon Development
Regulation Of Metabolic Process
Cell Morphogenesis Involved In Neuron Differentiation
Locomotion
Regulation Of Cellular Process
Axon Guidance
Neuron Projection Morphogenesis
Cell Development
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Anatomical Structure Morphogenesis
Cell Morphogenesis
Activin Receptor Signaling Pathway
Signal Transduction
Palate Development
Pattern Specification Process
Neuron Differentiation
Regulation Of Cell Projection Assembly
Fc Receptor Signaling Pathway
Neuron Projection Development
Immune Response-activating Cell Surface Receptor Signaling Pathway
Cell Fate Commitment
Signaling
Cell Projection Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Cell Part Morphogenesis
Regulation Of Signal Transduction
Cell Communication
Positive Regulation Of Cellular Component Biogenesis
Positive Regulation Of Signal Transduction
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Tissue Development
Regulation Of Nitrogen Compound Metabolic Process
Chemotaxis
Regulation Of Filopodium Assembly
Peptidyl-threonine Phosphorylation
Endocardial Cell Differentiation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Neuron Development
Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Cellular Response To Transforming Growth Factor Beta Stimulus
Tagcloud
?
19a
19b1
5p
apaf1
beclin1
daci
exerts
favor
hep3b
hepg2
hsa
impedance
inc
interfere
lbh589
mentioned
mimicking
mir30a
mirna
mirnas
oligonucleotides
oncomirs
panobinostat
periodicals
proving
qpcr
restoring
transfecting
wiley
Tagcloud (Difference)
?
19a
19b1
5p
apaf1
beclin1
daci
exerts
favor
hep3b
hepg2
hsa
impedance
inc
interfere
lbh589
mentioned
mimicking
mir30a
mirna
mirnas
oligonucleotides
oncomirs
panobinostat
periodicals
proving
qpcr
restoring
transfecting
wiley
Tagcloud (Intersection)
?