RHOJ and SSX3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RHOJ	SSX3
Description		ras homolog family member J	SSX family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome	Nucleus
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	Protein Binding
	Biological Process	Angiogenesis Endocytosis Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Shape Regulation Of Endothelial Cell Migration Establishment Of Cell Polarity Actin Cytoskeleton Organization Retina Vasculature Morphogenesis In Camera-type Eye Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis	Regulation Of DNA-templated Transcription
Pathways		RHOJ GTPase cycle
Drugs
Diseases
GWAS		Endometriosis ( 28881265) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)
Interacting Genes		22 interacting genes: ACVR1 ADAMTSL4 BHLHE40 BLZF1 BMPR1B CDC42 DOCK10 DOCK8 GOLGA2 MEOX2 PAK1 PAK3 PAK5 PAK6 PARD6B SMAD2 SMAD4 SSX3 TGFBR1 TRIP10 WAS ZNF426	22 interacting genes: AGTRAP AKAP9 CBY2 CEP63 CEP70 CMTM4 CMTM5 DDIT3 KRT27 MED4 MEOX2 MIPOL1 PCBD2 PIH1D2 RABGEF1 RHOJ SSX2IP ZBTB25 ZBTB3 ZNF496 ZNG1A ZSCAN1
Entrez ID		57381	10214
HPRD ID		09632	02265
Ensembl ID		ENSG00000126785	ENSG00000165584
Uniprot IDs		Q7Z513 Q9H4E5	Q99909
PDB IDs
Enriched GO Terms of Interacting Partners?		SMAD Binding Transforming Growth Factor Beta Receptor Activity, Type I Activin Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Activity Pattern Specification Process Protein Serine/threonine Kinase Activity Anatomical Structure Morphogenesis Cell Migration Ameboidal-type Cell Migration Positive Regulation Of Epithelial To Mesenchymal Transition Regionalization Cell Projection Morphogenesis Neuron Projection Morphogenesis I-SMAD Binding Dendritic Spine Morphogenesis Protein Kinase Activity Regulation Of Cell Motility Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Motility Roof Of Mouth Development Regulation Of Locomotion Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Projection Organization Regulation Of Actin Cytoskeleton Organization Intracellular Signal Transduction Activin Responsive Factor Complex Regulation Of Actin Filament-based Process Intracellular Signaling Cassette Regulation Of Stress Fiber Assembly Regulation Of Supramolecular Fiber Organization Kinase Activity Cellular Response To BMP Stimulus Transforming Growth Factor Beta Receptor Signaling Pathway Dendritic Spine Organization Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cell Migration Ventricular Septum Morphogenesis Regulation Of Actin Filament Organization Positive Regulation Of SMAD Protein Signal Transduction Tissue Development Neuron Projection Organization Postsynapse Organization Gastrulation Activin Receptor Complex Activin Receptor Activity, Type I SMAD Protein Complex Trophoblast Cell Migration Positive Regulation Of Stress Fiber Assembly
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